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Article
Circulating Hormones and Mammographic Density in Premenopausal Women
Prior research suggests that several endogenous hormones in premenopausal women are associated with breast cancer risk; however, few studies have evaluated associations of endogenous hormones with mammographic...
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Article
Alcohol Consumption and Urinary Estrogens and Estrogen Metabolites in Premenopausal Women
In a cross-sectional analysis, we evaluated the associations of usual total alcohol and wine intake with a comprehensive profile of mid-luteal phase urinary estrogens and estrogen metabolites (referred to join...
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Article
Alcohol Consumption and Risk of Breast Cancer by Tumor Receptor Expression
In epidemiologic studies, alcohol consumption appears more strongly associated with risk of estrogen receptor (ER)-positive than ER-negative breast cancer. However, this association has not been assessed by ot...
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Article
The Relationship Between Bilateral Oophorectomy and Plasma Hormone Levels in Postmenopausal Women
Oophorectomy prior to natural menopause reduces breast cancer risk. We evaluated whether timing of oophorectomy (during premenopause vs. postmenopause) or hysterectomy was associated with hormone levels, speci...
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Article
The Association of Reproductive and Lifestyle Factors with a Score of Multiple Endogenous Hormones
We recently reported that high levels of multiple sex and growth hormones were associated with increased postmenopausal breast cancer risk. Limited research has explored the relationship between reproductive, ...
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Article
Analgesic Use and Patterns of Estrogen Metabolism in Premenopausal Women
Analgesic use has been hypothesized to reduce the risk of some cancers, with inverse associations between analgesics and colon cancer, and suggestive inverse associations for breast cancer. Estrogen metabolite...
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Updates from the Editors
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Article
Body Size in Relation to Urinary Estrogens and Estrogen Metabolites (EM) Among Premenopausal Women during the Luteal Phase
Estrogen metabolism profiles may play an important role in the relationship between body size and breast carcinogenesis. Previously, we observed inverse associations between current body mass index (BMI) and p...
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Article
Dietary Fat, Fiber, and Carbohydrate Intake and Endogenous Hormone Levels in Premenopausal Women
The authors conducted a cross-sectional study to investigate the associations of fat, fiber, and carbohydrate intake with endogenous estrogen, androgen, and insulin-like growth factor (IGF) levels among 595 pr...
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Article
Circulating Sex Steroids and Breast Cancer Risk in Premenopausal Women
Evidence from both laboratory and epidemiologic studies indicate a key role of hormones in the etiology of breast cancer. In epidemiologic studies, indirect data, including the consistent associations observed...
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Article
Prolactin and Breast Cancer Etiology: An Epidemiologic Perspective
A number of epidemiologic studies of prolactin and breast cancer etiology have recently become available. Retrospective case-control studies have suggested a modest positive or null relationship between circul...
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Chapter
Circulating Levels of Sex Steroids and Prolactin in Premenopausal Women and Risk of Breast Cancer
The key role of the hormonal environment in breast cancer (BC) etiology is well documented. Reproductive factors such as parity and age at menopause influence BC risk and postmenopausal hormone use increases r...