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Article
Open AccessFacemask acne attenuation through modulation of indirect microbiome interactions
During the COVID-19 pandemic, facemasks played a pivotal role in preventing person-person droplet transmission of viral particles. However, prolonged facemask wearing causes skin irritations colloquially refer...
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Article
Optoelectronic Synapse Behaviors of HfS2 Grown via Molten Salt Flux Method
Layered two-dimensional materials are promising candidates for next-generation semiconductor platforms owing to their atomically thin bodies, and it is crucial to develop a method for their large-scale synthes...
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Article
Open AccessDurvalumab plus pazopanib combination in patients with advanced soft tissue sarcomas: a phase II trial
We aimed to determine the activity of the anti-VEGF receptor tyrosine-kinase inhibitor, pazopanib, combined with the anti-PD-L1 inhibitor, durvalumab, in metastatic and/or recurrent soft tissue sarcoma (STS). ...
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Chapter and Conference Paper
A Study on the Pressure Sensor for Estimating the Load Point in a Prosthetic Socket
A transfemoral prosthesis is a device that performs locomotion in place of the amputated lower leg. It is necessary to change the locomotion style suitable for each environment in order to cope with the locomo...
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Article
Open AccessDevelopment of an offline OOH advertising recommendation system using negative sampling and deep interest network
The out-of-home (OOH) advertising market has been operated exclusively following the know-how of salespeople. Thus, it is difficult to make scientific decisions and systematically provide various options to ad...
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Article
Targeting tumor-intrinsic PD-L1 suppresses the progression and aggressiveness of head and neck cancer by inhibiting GSK3β-dependent Snail degradation
PD-L1 is an immune checkpoint protein that allows cells to evade T-cell-mediated immune responses. Herein, we uncover a tumor-intrinsic mechanism of PD-L1 that is responsible for the progression and aggressiv...
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Article
Open AccessInhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH
11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) is a key enzyme that catalyzes the intracellular conversion of cortisone to physiologically active cortisol. Although 11βHSD1 has been implicated in numerous m...
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Article
Open AccessAnonymous view on transgender soldiers: content analysis of online news headlines and comments in South Korea
The inclusion of transgender soldiers in the military service raises a fundamental question about the dichotomous categorization of human sexes based on anatomy and gender role within a specialized organizatio...
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Article
Properties and anti-inflammatory effects of Sargassum muticum enzymatic extracts decomposed using crude enzyme from Shewanella oneidensis PKA1008
This study was conducted to investigate the general properties of an enzymatic extract of Sargassum muticum (SM) produced using a crude enzyme from Shewanella oneidensis PKA 1008 and their anti-inflammatory activ...
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Article
Open AccessIncreased pulsatility index of the basilar artery is a risk factor for neurological deterioration after stroke: a case control study
Higher pulsatility of the middle cerebral artery (MCA) is known to be associated with stroke progression. We investigated whether pulsatility index (PI) of the basilar artery (BA) can predict neurological dete...
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Article
Fluorescence-activated cell sorting-mediated directed evolution of Wickerhamomyces ciferrii for enhanced production of tetraacetyl phytosphingosine
Ceramides are a major lipid class known to play an essential role in maintaining skin function. Thus, efforts have been made to produce ceramides and ceramide precursors in large quantities for industrial appl...
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Article
Open AccessHER2 expression, copy number variation and survival outcomes in HER2-low non-metastatic breast cancer: an international multicentre cohort study and TCGA-METABRIC analysis
HER2-low breast cancer (BC) is currently an area of active interest. This study evaluated the impact of low expression of HER2 on survival outcomes in HER2-negative non-metastatic breast cancer (BC).
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Article
Characterization of Sargassum patens C. Agardh Enzymatic Extracts Using Crude Enzyme from Shewanella oneidensis PKA 1008 and Their Anti-inflammatory Effects
This study was conducted to investigate the physicochemical properties and anti-inflammatory effects of the enzymatic extracts of Sargassum patens C. Agardh (SP) using crude enzyme from Shewanella oneidensis PKA ...
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Article
Open AccessA novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthritis via reciprocal regulation of Th17 and Treg cells
The interleukin (IL)-12 cytokine family is closely related to the development of T helper cells, which are responsible for autoimmune disease enhancement or suppression. IL-12 family members are generally hete...
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Article
Open AccessCorrelation between cardiopulmonary metabolic energy cost and lower-limb muscle activity during inclined treadmill gait in older adults
Inclined walking requires more cardiopulmonary metabolic energy and muscle strength than flat-level walking. This study sought to investigate changes in lower-limb muscle activity and cardiopulmonary metabolic...
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Article
Open AccessDevelopment of a quantitative prediction algorithm for target organ-specific similarity of human pluripotent stem cell-derived organoids and cells
Human pluripotent stem cell (hPSC)-derived organoids and cells have similar characteristics to human organs and tissues. Thus, in vitro human organoids and cells serve as a superior alternative to conventional...
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Article
Diagnosis of Unusual Case of Dysphagia with Macroglossia and Rigid Tongue
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Article
Determination of Similarity Cutoff Value for the Classification of Macrobenthic Communities in the Korean Coast
The selection of optimal cutoff points has been questioned in many cluster analyses. Here, we aimed to determine a percent similarity cutoff value that can be generally applied to macrobenthic community classi...
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Article
Generation of Hepatic Progenitor Cells from the Primary Hepatocytes of Nonhuman Primates Using Small Molecules
Since primates have more biological similarities to humans than do other animals, they are a valuable resource in various field of research, including biomedicine, regenerative medicine, and drug discovery. Ho...
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Article
Open AccessHypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss
Aging is associated with cellular senescence followed by bone loss leading to bone fragility in humans. However, the regulators associated with cellular senescence in aged bones need to be identified. Hypoxia-...
