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  1. Article

    Open Access

    A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine

    Coronavirus disease-19 (Covid-19) pandemic have demonstrated the importantance of vaccines in disease prevention. Self-amplifying mRNA vaccines could be another option for disease prevention if demonstrated to...

    Jenny G. Low, Ruklanthi de Alwis, Shiwei Chen, Shirin Kalimuddin… in npj Vaccines (2022)

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  2. Article

    Open Access

    Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccine

    Remarkable potency has been demonstrated for mRNA vaccines in reducing the global burden of the ongoing COVID-19 pandemic. An alternative form of the mRNA vaccine is the self-amplifying mRNA (sa-mRNA) vaccine,...

    Eugenia Z. Ong, Jia **n Yee, Justin S. G. Ooi, Ayesa Syenina… in npj Vaccines (2022)

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