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  1. Article

    Open Access

    Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals

    Currently, the best clinical predictor for inflammatory bowel disease (IBD) is family history. Over 163 sequence variants have been associated with IBD in genome-wide association studies, but they have weak ef...

    Anna B Stittrich, Justin Ashworth, Mude Shi, Max Robinson… in Human Genome Variation (2016)

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  2. No Access

    Article

    Dense genoty** of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

    Anne Hinks and colleagues identify 14 new susceptibility loci for juvenile idiopathic arthritis through targeted analyses of genomic regions implicated in immune function. Their study implicates several pathwa...

    Anne Hinks, Joanna Cobb, Miranda C Marion, Sampath Prahalad, Marc Sudman… in Nature Genetics (2013)

  3. Article

    Correction: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

    Nat. Genet. 43, 246–252 (2011); published online 6 February 2011; corrected after print 11 August 2011 In the version of this article initially published, an affiliation was missing for two authors, Maria Gazo...

    Carl A Anderson, Gabrielle Boucher, Charlie W Lees, Andre Franke… in Nature Genetics (2011)

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  4. No Access

    Article

    Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

    John Rioux and colleagues report results of a large genome-wide association meta-analysis and follow-up study of ulcerative colitis. They identify 29 new risk loci for this inflammatory disease and show that m...

    Carl A Anderson, Gabrielle Boucher, Charlie W Lees, Andre Franke… in Nature Genetics (2011)

  5. No Access

    Article

    Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Miles Parkes and colleagues report results of a large genome-wide association meta-analysis and replication study for Crohn's disease. They identify 30 new susceptibility loci for this inflammatory bowel disea...

    Andre Franke, Dermot P B McGovern, Jeffrey C Barrett, Kai Wang… in Nature Genetics (2010)

  6. No Access

    Article

    Common variants at five new loci associated with early-onset inflammatory bowel disease

    Hakon Hakonarson and colleagues report the discovery of five new regions associated with susceptibility to early-onset inflammatory bowel disease. They also identify multiple loci previously implicated in the ...

    Marcin Imielinski, Robert N Baldassano, Anne Griffiths… in Nature Genetics (2009)

  7. No Access

    Article

    Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

    The Collaborative Association Study of Psoriasis, in partnership with the Genetic Association Information Network (GAIN), reports a genome-wide association study for psoriasis. They identify new replicated ass...

    Rajan P Nair, Kristina Callis Duffin, Cynthia Helms, Jun Ding… in Nature Genetics (2009)

  8. No Access

    Article

    Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

    Hakon Hakonarson and colleagues report the identification of two new susceptibility loci for inflammatory bowel disease (IBD). One variant is near a gene encoding tumor necrosis factor receptor subfamily membe...

    Subra Kugathasan, Robert N Baldassano, Jonathan P Bradfield… in Nature Genetics (2008)