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  1. Article

    Open Access

    Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation

    Intercellular communication between axons and Schwann cells is critical for attaining the complex morphological steps necessary for axon maturation. In the early onset motor neuron disease spinal muscular atro...

    Lingling Kong, Cera W. Hassinan, Florian Gerstner… in Acta Neuropathologica Communications (2023)

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  2. Article

    Open Access

    Kinetic modeling of tumor regression incorporating the concept of cancer stem-like cells for patients with locally advanced lung cancer

    Personalized medicine for patients receiving radiation therapy remains an elusive goal due, in part, to the limits in our understanding of the underlying mechanisms governing tumor response to radiation. The p...

    Hualiang Zhong, Stephen Brown… in Theoretical Biology and Medical Modelling (2018)

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  3. Article

    Open Access

    ACTA2 mutation and postpartum hemorrhage: a case report

    ACTA2 encodes smooth muscle specific α-actin, a critical component or the contractile complex of vascular smooth muscle. Mutations in ACTA2 are the most common genetic cause of thoraci...

    Kylie Cooper, Stephen Brown in BMC Medical Genetics (2017)

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  4. No Access

    Article

    Mutations in the pre-replication complex cause Meier-Gorlin syndrome

    Andrew Jackson, Ernie Bongers and colleagues report the identification of mutations in five genes in individuals with Meier-Gorlin syndrome. The five genes, ORC1, ORC4, ORC6, CDT1 and CDC6, all encode components ...

    Louise S Bicknell, Ernie M H F Bongers, Andrea Leitch, Stephen Brown… in Nature Genetics (2011)

  5. No Access

    Chapter

    Gene Therapy of Prostate Cancer

    Gene therapy has been administered to over 1,000 men with prostate cancer. Overall, it has been associated with little toxicity when administered as a single agent or in combination with standard prostate canc...

    Svend O. Freytag, Hans Stricker, Benjamin Movsas… in Gene-Based Therapies for Cancer (2010)

  6. Article

    Open Access

    Radiation-induced skin injury in the animal model of scleroderma: implications for post-radiotherapy fibrosis

    Radiation therapy is generally contraindicated for cancer patients with collagen vascular diseases (CVD) such as scleroderma due to an increased risk of fibrosis. The tight skin (TSK) mouse has skin which, in ...

    Sanath Kumar, Andrew Kolozsvary, Robert Kohl, Mei Lu, Stephen Brown… in Radiation Oncology (2008)

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  7. Article

    Open Access

    Auto-augmentation: ought it to be done?

    Suzanne Lawther, David Marshall, Alan Bailie, Stephen Brown in Cerebrospinal Fluid Research (2007)

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  8. Article

    Open Access

    50th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida

    Stephen Brown in Cerebrospinal Fluid Research (2006)

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  9. Article

    Open Access

    49th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida

    Stephen Brown in Cerebrospinal Fluid Research (2005)

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