7 Result(s)
within
Stephanie Longet
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessSerological evidence of zoonotic filovirus exposure among bushmeat hunters in Guinea
Human Ebola virus (EBOV) outbreaks caused by persistent EBOV infection raises questions on the role of zoonotic spillover in filovirus epidemiology. To characterise filovirus zoonotic exposure, we collected cr...
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Article
Open AccessOmicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history
Pronounced immune escape by the SARS-CoV-2 Omicron variant has resulted in many individuals possessing hybrid immunity, generated through a combination of vaccination and infection. Concerns have been raised t...
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Article
Open AccessDivergent trajectories of antiviral memory after SARS-CoV-2 infection
The trajectories of acquired immunity to severe acute respiratory syndrome coronavirus 2 infection are not fully understood. We present a detailed longitudinal cohort study of UK healthcare workers prior to va...
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Article
Open AccessTwo doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
The extent to which immune responses to natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and immunization with vaccines protect against variants of concern (VOC) is of increa...
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Article
Open AccessComparison of rhesus and cynomolgus macaques as an infection model for COVID-19
A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to understand the pathogenesis o...
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Article
Open AccessDose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity
There is a vital need for authentic COVID-19 animal models to enable the pre-clinical evaluation of candidate vaccines and therapeutics. Here we report a dose titration study of SARS-CoV-2 in the ferret model....
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Article
Open AccessPseudoty** of VSV with Ebola virus glycoprotein is superior to HIV-1 for the assessment of neutralising antibodies
Ebola virus (EBOV) is an enveloped, single-stranded RNA virus that can cause Ebola virus disease (EVD). It is thought that EVD survivors are protected against subsequent infection with EBOV and that neutralisi...
