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  1. Article

    Open Access

    Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners

    Complex II (CII) activity controls phenomena that require crosstalk between metabolism and signaling, including neurodegeneration, cancer metabolism, immune activation, and ischemia-reperfusion injury. CII act...

    Pankaj Sharma, Elena Maklashina, Markus Voehler, Sona Balintova in Nature Communications (2024)

  2. Article

    Open Access

    Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints

    Cell growth and survival depend on a delicate balance between energy production and synthesis of metabolites. Here, we provide evidence that an alternative mitochondrial complex II (CII) assembly, designated a...

    Ayenachew Bezawork-Geleta, He Wen, LanFeng Dong, Bing Yan in Nature Communications (2018)