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Early post-natal life stress induces permanent adrenocorticotropin-dependent hypercortisolism in male mice

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  1. Article

    Open Access

    CSF tau is associated with impaired cortical plasticity, cognitive decline and astrocyte survival only in APOE4-positive Alzheimer’s disease

    In Alzheimer’s disease (AD) patients, apopoliprotein (APOE) polymorphism is the main genetic factor associated with more aggressive clinical course. However, the interaction between cerebrospinal fluid (CSF) t...

    Giacomo Koch, Francesco Di Lorenzo, Stefano Loizzo, Caterina Motta in Scientific Reports (2017)

  2. Article

    Open Access

    Visual evoked potentials of Niemann-Pick type C1 mice reveal an impairment of the visual pathway that is rescued by 2-hydroxypropyl-ß-cyclodextrin

    The lysosomal storage disorder, Niemann Pick type C1 (NPC1), presents a variable phenotype including neurovisceral and neurological symptoms. 2-Hydroxypropyl-ß-cyclodextrin (HPßCD)-based therapies are presentl...

    Giampiero Palladino, Stefano Loizzo, Andrea Fortuna in Orphanet Journal of Rare Diseases (2015)

  3. Article

    Overweight and Metabolic and Hormonal Parameter Disruption Are Induced in Adult Male Mice by Manipulations During Lactation Period

    Neonatal manipulations (10 min of maternal separation plus s.c. sham injection, daily for the first 21 d of life) determine overweight in male adult mice. In this work, we investigated the mechanisms underlyin...

    Alberto Loizzo, Stefano Loizzo, Gabriella Galietta, Stefania Caiola in Pediatric Research (2006)