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  1. Article

    Open Access

    Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells

    Rare multipotent stem cells replenish millions of blood cells per second through a time-consuming process, passing through multiple stages of increasingly lineage-restricted progenitors. Although insults to th...

    Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen in Nature Immunology (2024)

  2. Article

    Open Access

    T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes

    Unlike chimeric antigen receptors, T-cell receptors (TCRs) can recognize intracellular targets presented on human leukocyte antigen (HLA) molecules. Here we demonstrate that T cells expressing TCRs specific fo...

    Muhammad Ali, Eirini Giannakopoulou, Yingqian Li in Nature Biotechnology (2022)