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Article
Open AccessAlternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells
Rare multipotent stem cells replenish millions of blood cells per second through a time-consuming process, passing through multiple stages of increasingly lineage-restricted progenitors. Although insults to th...
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Article
Open AccessT cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Unlike chimeric antigen receptors, T-cell receptors (TCRs) can recognize intracellular targets presented on human leukocyte antigen (HLA) molecules. Here we demonstrate that T cells expressing TCRs specific fo...