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    Open Access

    T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes

    Unlike chimeric antigen receptors, T-cell receptors (TCRs) can recognize intracellular targets presented on human leukocyte antigen (HLA) molecules. Here we demonstrate that T cells expressing TCRs specific fo...

    Muhammad Ali, Eirini Giannakopoulou, Yingqian Li… in Nature Biotechnology (2022)

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