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  1. No Access

    Article

    Antiseptic Effects of New 3′-N-Substituted Carbazole Derivatives In Vitro and In Vivo

    Inhibition of high-mobility group box 1 (HMGB1) protein and restoration of endothelial integrity are emerging as attractive therapeutic strategies in the management of sepsis. Here, new five structurally relat...

    Wonhwa Lee, Soyoung Kwak, Eunju Yun, Jee Hyun Lee, MinKyun Na… in Inflammation (2015)

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    Article

    Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) Inhibits High Glucose-Induced Inflammation In Vitro and In Vivo

    Vascular inflammation plays a key role in the initiation and progression of atherosclerosis, a major complication of diabetes mellitus. Aspalathin (Asp) and nothofagin (Not) are two major active dihydrochalcon...

    Sae-Kwang Ku, Soyoung Kwak, Yaesol Kim, Jong-Sup Bae in Inflammation (2015)

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    Article

    Orientin Inhibits High Glucose-Induced Vascular Inflammation In Vitro and In Vivo

    Vascular inflammation plays a key role in the initiation and progression of atherosclerosis, a major complication of diabetes mellitus. Orientin, a C-glycosyl flavonoid, is known to have anxiolytic and antioxidat...

    Sae-Kwang Ku, Soyoung Kwak, Jong-Sup Bae in Inflammation (2014)

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    Article

    Hyperoside Inhibits High-Glucose-Induced Vascular Inflammation In Vitro and In Vivo

    Hyperoside, an active compound from the genera of Hypericum and Crataegus, was reported to have antioxidant, antihyperglycemic, anticancer, anti-inflammatory, and anticoagulant activities. Vascular inflammatory p...

    Sae-Kwang Ku, Soyoung Kwak, O-Jun Kwon, Jong-Sup Bae in Inflammation (2014)