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  1. Article

    Open Access

    Sociobiome - Individual and neighborhood socioeconomic status influence the gut microbiome in a multi-ethnic population in the US

    Lower socioeconomic status (SES) is related to increased incidence and mortality due to chronic diseases in adults. Association between SES variables and gut microbiome variation has been observed in adults at...

    Soyoung Kwak, Mykhaylo Usyk, Dia Beggs, Heesun Choi in npj Biofilms and Microbiomes (2024)

  2. Article

    Open Access

    Usefulness of barium sulfate and iohexol as contrast agents for VFSS in visualizing components of swallowing predictable of poor outcomes

    Barium sulfate and iohexol are commonly used as contrast agents for videofluoroscopic swallowing study (VFSS). This study compared their usefulness as contrast agents in visualizing components of swallowing pr...

    Min Soo Kang, Min Cheol Chang, Soyoung Kwak in Scientific Reports (2023)

  3. Article

    Open Access

    Exploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans

    Previous studies have indicated an association of higher alcohol intake with cardiovascular disease and related traits, but causation has not been definitively established. In this study, the causal effect of ...

    Yoonsu Cho, Soyoung Kwak, Sarah J. Lewis, Kaitlin H. Wade in Scientific Reports (2018)

  4. No Access

    Article

    Antiseptic Effects of New 3′-N-Substituted Carbazole Derivatives In Vitro and In Vivo

    Inhibition of high-mobility group box 1 (HMGB1) protein and restoration of endothelial integrity are emerging as attractive therapeutic strategies in the management of sepsis. Here, new five structurally relat...

    Wonhwa Lee, Soyoung Kwak, Eunju Yun, Jee Hyun Lee, MinKyun Na in Inflammation (2015)

  5. No Access

    Article

    Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) Inhibits High Glucose-Induced Inflammation In Vitro and In Vivo

    Vascular inflammation plays a key role in the initiation and progression of atherosclerosis, a major complication of diabetes mellitus. Aspalathin (Asp) and nothofagin (Not) are two major active dihydrochalcon...

    Sae-Kwang Ku, Soyoung Kwak, Yaesol Kim, Jong-Sup Bae in Inflammation (2015)

  6. No Access

    Article

    Orientin Inhibits High Glucose-Induced Vascular Inflammation In Vitro and In Vivo

    Vascular inflammation plays a key role in the initiation and progression of atherosclerosis, a major complication of diabetes mellitus. Orientin, a C-glycosyl flavonoid, is known to have anxiolytic and antioxidat...

    Sae-Kwang Ku, Soyoung Kwak, Jong-Sup Bae in Inflammation (2014)

  7. No Access

    Article

    Hyperoside Inhibits High-Glucose-Induced Vascular Inflammation In Vitro and In Vivo

    Hyperoside, an active compound from the genera of Hypericum and Crataegus, was reported to have antioxidant, antihyperglycemic, anticancer, anti-inflammatory, and anticoagulant activities. Vascular inflammatory p...

    Sae-Kwang Ku, Soyoung Kwak, O-Jun Kwon, Jong-Sup Bae in Inflammation (2014)

  8. No Access

    Article

    Fisetin inhibits high-glucose-induced vascular inflammation in vitro and in vivo

    Fisetin, an active compound isolated from flowering plants in the family Fabaceae, was reported to have antiviral, neuroprotective, and anti-inflammatory effects. Vascular inflammatory processes have been sugg...

    Soyoung Kwak, Sae-Kwang Ku, Jong-Sup Bae in Inflammation Research (2014)

  9. No Access

    Article

    Antiplatelet, anticoagulant, and profibrinolytic activities of cudratricusxanthone A

    Cudratricusxanthone A (CTXA), a natural bioactive compound extracted from the roots of Cudrania tricuspidata Bureau, is known to possess hepatoprotective, antiproliferative and anti-inflammatory activities. Howev...

    Hayoung Yoo, Sae-Kwang Ku, Wonhwa Lee, Soyoung Kwak in Archives of Pharmacal Research (2014)