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  1. Article

    Open Access

    Genetic diversity of variants involved in drug response among Tunisian and Italian populations toward personalized medicine

    Adverse drug reactions (ADR) represent a significant contributor to morbidity and mortality, imposing a substantial financial burden. Genetic ancestry plays a crucial role in drug response. The aim of this stu...

    Haifa Jmel, Stefania Sarno, Cristina Giuliani, Wided Boukhalfa in Scientific Reports (2024)

  2. Article

    Open Access

    Ethnic and functional differentiation of copy number polymorphisms in Tunisian and HapMap population unveils insights on genome organizational plasticity

    Admixture map** has been useful in identifying genetic variations linked to phenotypes, adaptation and diseases. Copy number variations (CNVs) represents genomic structural variants spanning large regions of...

    Lilia Romdhane, Sameh Kefi, Nessrine Mezzi, Najla Abassi, Haifa Jmel in Scientific Reports (2024)

  3. Article

    Open Access

    Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions

    Diabetes and hypertension are a serious public health problem worldwide. In the last decades, prevalence of these two metabolic diseases has dramatically increased in the Middle East and North Africa region, e...

    Nadia Kheriji, Thouraya Dakhlaoui, Wafa Kamoun Rebai, Sonia Maatoug in Scientific Reports (2023)

  4. Article

    Open Access

    Inflammatory landscape in Xeroderma pigmentosum patients with cutaneous melanoma

    Xeroderma pigmentosum (XP) is a DNA repair disease that predisposes to early skin cancers as cutaneous melanoma. Melanoma microenvironment contains inflammatory mediators, which would be interesting biomarkers...

    Asma Chikhaoui, Meriem Jones, Tadeja Režen, Melika Ben Ahmed in Scientific Reports (2022)