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  1. Article

    Open Access

    Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells

    The Ras pathway genes KRAS, BRAF, or ERBBs have somatic mutations in ~ 60% of human colorectal carcinomas. At present, it is unknown whether the remaining cases lack mutations activating the Ras pathway or whethe...

    Snehangshu Kundu, Muhammad Akhtar Ali, Niklas Handin, Narendra Padhan in Genome Medicine (2018)