9 Result(s)
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Open AccessDeep analysis and optimization of CARD antibiotic resistance gene discovery models
Identification of antibiotic resistance genes from environmental samples has been a critical sub-domain of gene discovery which is directly connected to human health. However, it is drawing extraordinary atten...
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Open AccessImproving somatic variant identification through integration of genome and exome data
Cost-effective high-throughput sequencing technologies, together with efficient map** and variant calling tools, have made it possible to identify somatic variants for cancer study. However, integrating soma...
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Open AccessBASE: a practical de novo assembler for large genomes using long NGS reads
De novo genome assembly using NGS data remains a computation-intensive task especially for large genomes. In practice, efficiency is often a primary concern and favors using a more eff...
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Open AccessGIW and InCoB, two premier bioinformatics conferences in Asia with a combined 40 years of history
Knowledge discovery in bioinformatics thrives on joint and inclusive efforts of stakeholders. Similarly, knowledge dissemination is expected to be more effective and scalable through joint efforts. Therefore, ...
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Open AccessGlobal small RNA analysis in fast-growing Arabidopsis thaliana with elevated concentrations of ATP and sugars
In higher eukaryotes, small RNAs play a role in regulating gene expression. Overexpression (OE) lines of Arabidopsis thaliana purple acid phosphatase 2 (AtPAP2) were shown to grow faster and exhibit higher ATP an...
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Open AccessMetaCluster-TA: taxonomic annotation for metagenomic data based on assembly-assisted binning
Taxonomic annotation of reads is an important problem in metagenomic analysis. Existing annotation tools, which rely on the approach of aligning each read to the taxonomic structure, are unable to annotate man...
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Open AccessDe novo assembly and characterization of Camelina sativatranscriptome by paired-end sequencing
Biofuels extracted from the seeds of Camelina sativa have recently been used successfully as environmentally friendly jet-fuel to reduce greenhouse gas emissions. Camelina sativa is genetically very close to Arab...
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Open AccessRefining orthologue groups at the transcript level
Orthologues are genes in different species that are related through divergent evolution from a common ancestor and are expected to have similar functions. Many databases have been created to describe orthologo...
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Open AccessPromoter-sharing by different genes in human genome – CPNE1 and RBM12 gene pair as an example
Regulation of gene expression plays important role in cellular functions. Co-regulation of different genes may indicate functional connection or even physical interaction between gene products. Thus analysis o...
