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  1. No Access

    Article

    Ambra1 in cancer: implications for clinical oncology

    Activating molecule in Beclin-1-regulated autophagy protein 1 (Ambra1) is well known to mediate the autophagy process and promote the formation of autophagosomes. In addition, Ambra1 is involved in the executi...

    Yan-qiu Qin, Si-yu Liu, Mei-ling Lv, Wei-liang Sun in Apoptosis (2022)

  2. Article

    Open Access

    The ASIC3-M-CSF-M2 macrophage-positive feedback loop modulates fibroblast-to-myofibroblast differentiation in skin fibrosis pathogenesis

    Inflammation is one of the main pathological features leading to skin fibrosis and a key factor leading to the progression of skin fibrosis. Acidosis caused by a decrease in extracellular pH is a sign of the i...

    Jun-Jie Wu, Zi-Li Sun, Si-Yu Liu, Zhong-Hua Chen, Zheng-Dong Yuan… in Cell Death & Disease (2022)

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  3. No Access

    Article

    Ambra1 regulates apoptosis and chemosensitivity in breast cancer cells through the Akt-FoxO1-Bim pathway

    The sensitivity of cells to chemotherapeutic agents has a major effect on disease outcome in breast cancer patients. Unfortunately, there are numerous factors involved in the regulation of chemosensitivity, an...

    Wei-liang Sun, Ling-yan He, Li Liang, Si-yu Liu, Jie Luo, Mei-ling Lv… in Apoptosis (2022)

  4. No Access

    Article

    Matairesinol Suppresses Neuroinflammation and Migration Associated with Src and ERK1/2-NF-κB Pathway in Activating BV2 Microglia

    Chronic neuroinflammation is a pathological feature of neurodegenerative diseases. Inhibition of microglia-mediated neuroinflammation might be a potential strategy for neurodegeneration. Matairesinol, a dibenz...

    Peng Xu, Meng-Wei Huang, Chen-** **ao, Fen Long, Ying Wang… in Neurochemical Research (2017)

  5. No Access

    Article

    (7R,8S)-Dehydrodiconiferyl Alcohol Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia by Inhibiting MAPK Signaling

    (7R,8S)-Dehydrodiconiferyl alcohol (DDA), a lignan isolated from the dried stems of Clematis armandii, has been found to exert potential anti-inflammatory activity in vitro. In the present study, we investigated ...

    Si-Yu Liu, Peng Xu, **ao-Ling Luo, **-Feng Hu, **n-Hua Liu in Neurochemical Research (2016)