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115 Result(s)
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Article
Post-operative staging and survival based on the revised tnm staging system for non-small cell lung cancer
Objective: To study the factors affecting post-operative staging and survival in non-small cell lung cancer (NSCLC) patients based on the revised TNM staging system adopted by the UICC in 1977. Methods: Data w...
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Expression of heparanase and its clinical significance in human non-small cell lung cancer
Objective: To explore the expression and significance of heparanase in non-small cell lung cancer (NSCLC) regarding prognosis and clinicopathological parameters. Methods: The expression of hepara...
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Article
Efficacy of ifosfamide and VP-16 (etoposide) in patients with small cell lung cancer and the correlation between microvessel count on chemosensitivity
To evaluate the efficacy of ifosfamide and etoposide (VP-16) in patients with small cell lung cancer (SCLC), and investigate the correlation between microvessel count (MVC) in tumor and chemotherapeutic sensit...
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A prospective randomized study of adjuvant chemotherapy in completely resected stage III-N2 non small cell lung cancer
To evaluate the effect of postoperative adjuvant chemotherapy on survival after complete resection of stage III-N2 non-small-cell lung cancer.
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Article
Inhibition of HOXB7 gene expression in melanoma cells by small interfering RNA
HOXB7 gene is a kind of transcription regulator over-expressed in malignant melanoma (MM) cell lines. It can specifically up-regulate the expression of angiogenic factors and tumor growth factors such as bFGF,...
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Article
Huperzine A Activates Wnt/β-Catenin Signaling and Enhances the Nonamyloidogenic Pathway in an Alzheimer Transgenic Mouse Model
Huperzine A (HupA) is a reversible and selective inhibitor of acetylcholinesterase (AChE), and it has multiple targets when used for Alzheimer's disease (AD) therapy. In this study, we searched for new mechani...
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Article
Role of Glycine Receptors in Glycine-Induced LTD in Hippocampal CA1 Pyramidal Neurons
Glycine in the hippocampus can exert its effect on both synaptic NMDA receptors (NMDARs) and extrasynaptic functional glycine receptors (GlyRs) via distinct binding sites. Previous studies have reported that g...
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Article
Clinical practice guideline of Chinese medicine for chronic gastritis
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Article
Lead powder use for skin care and elevated blood lead level among children in a Chinese rural area
To investigate the association between lead powder use, as folk skin care, and blood lead level (BLL) in children, we studied 222 children up to 14-years old living in a Chinese rural area and administered a f...
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Article
Silencing endothelin-3 expression attenuates the malignant behaviors of human melanoma cells by regulating SPARC levels
Endothelin-3 (ET-3) is aberrantly expressed in both metastatic melanoma tissues and cultured melanoma cells. Our previous work showed that ET-3 could promote survival of metastatic melanoma cells via its alter...
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Article
Effects of Fengbaisan (丰白散) on the expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in lung tissue of rats with chronic obstructive pulmonary disease
To observe effects of Fengbaisan (丰白散, FBS) on the expression of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in lung tissue of rats with chronic obstructive pulmonar...
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Article
Expression profiling of MicroRNAs in hippocampus of rats following traumatic brain injury
The changes of microRNA expression in rat hippocampus after traumatic brain injury (TBI) were explored. Adult SD rats received a single controlled cortical impact injury, and the ipsilateral hippocampus was ha...
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Article
Shenfu Injection (参附注射液) suppresses inflammation by targeting haptoglobin and pentraxin 3 in rats with chronic ischemic heart failure
To investigate the regulatory effects of Shenfu Injection (SFI, 参附注射液) on hemodynamic parameters and serum proteins in rats with post-infarction chronic heart failure (CHF).
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Article
Open AccessEfficacy and safety of mineralocorticoid receptor antagonists for patients with heart failure and diabetes mellitus: a systematic review and meta-analysis
The aim of this study was to systematically assess the efficacy and safety of mineralocorticoid receptor antagonists (MRAs) for patients with heart failure (HF) and diabetes mellitus (DM).
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Article
Study on diagnosis criteria of fire-heat syndrome based on receiver operating characteristic curve and principal component analysis
To establish the diagnostic quantitative criteria for fire-heat syndrome (FHS) of Chinese medicine (CM) based on the receiver operating characteristic (ROC) curve and principal component analysis (PCA).
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Article
Role of heteroplasmic mutations in the mitochondrial genome and the ID4 gene promoter methylation region in the pathogenesis of chronic aplastic anemia in patients suffering from Kidney yin deficiency
To analyze changes in gene amplification in the mitochondrial genome and in the ID4 gene promoter methylation region in patients with chronic aplastic anemia (CAA) suffering from Kidney (Shen) yin deficiency o...
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Article
Pro-angiogenic activity of notoginsenoside R1 in human umbilical vein endothelial cells in vitro and in a chemical-induced blood vessel loss model of zebrafish in vivo
This study aimed at investigating whether notoginsenoside R1 (R1), a unique saponin found in Panax notoginseng could promote angiogenic activity on human umbilical vein endothelial cells (HUVECs) and elucidate th...
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Article
Effects on the tumor specific growth factor and tumor necrosis factor α in rats’ precancerous lesion of primary hepatocellular carcinoma by direct moxibustion at Ganshu (BL 18) acupoint
To investigate the effect of direct moxibustion at Ganshu (BL18) on the serum concentrations of tumor specific growth factor (TSGF) and tumor necrosis factor α (TNF-α) in a rat model with precancerous lesion o...
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Article
Decreased mRNA levels of cardiac Cx43 and ZO1 in sudden cardiac death related to coronary atherosclerosis: a pilot study
Sudden cardiac death (SCD) is the most frequent cause of sudden unexplained death in forensic practice. The most common cause of SCD is coronary artery disease related to coronary atherosclerosis. Previous stu...
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Open AccessA multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Tong Luo Hua Shi capsule, a modernized Tibetan medicine, in patients with rheumatoid arthritis
Tong Luo Hua Shi (TLHS) is a new formulation of the traditional Tibetan medicine Wu-wei-gan-lu that has been used for the treatment of rheumatoid arthritis (RA) for hundreds of years in China. This study aimed...