13 Result(s)

Article

Erratum to: Study on the purification of polysaccharides from Noscoc flagelliforme with radial flow chromatography

Yu-Jie Dai, **g-Wen Wang, Shi-Ru Jia… in Biotechnology and Bioprocess Engineering (2009)

Article

Systematic engineering of the central metabolism in Escherichia coli for effective production of n-butanol

Microbes have been extensively explored for production of environment-friendly fuels and chemicals. The microbial fermentation pathways leading to these commodities usually involve many redox reactions. This m...

Mukesh Saini, Si-Yu Li, Ze Win Wang, Chung-Jen Chiang… in Biotechnology for Biofuels (2016)

Article

Enhance transgene responses through improving cellular uptake and intracellular trafficking by bio-inspired non-viral vectors

Gene therapy remains a significant challenge due to lots of barriers limiting the genetic manipulation technologies. As for non-viral delivery vectors, they often suffer insufficient performance due to inadequ...

**-** Ma, **g-Liang Xu, Yi-Yang Jia, Ya-Xuan Zhang… in Journal of Nanobiotechnology (2020)

Article

TAG pathway engineering via GPAT2 concurrently potentiates abiotic stress tolerance and oleaginicity in Phaeodactylum tricornutum

Despite the great potential of marine diatoms in biofuel sector, commercially viable biofuel production from native diatom strain is impractical. Targeted engineering of TAG pathway represents a promising appr...

**ang Wang, Si-Fen Liu, Ruo-Yu Li, Wei-Dong Yang… in Biotechnology for Biofuels (2020)

Article

Engineering prokaryotic regulator IrrE to enhance stress tolerance in budding yeast

Stress tolerance is one of the important desired microbial traits for industrial bioprocesses, and global regulatory protein engineering is an efficient approach to improve strain tolerance. In our study, IrrE...

Li Wang, **n Wang, Zhi-Qiang He, Si-Jie Zhou, Li Xu… in Biotechnology for Biofuels (2020)

Article

Cell-based and cell-free biocatalysis for the production of d-glucaric acid

d-Glucaric acid (GA) is a value-added chemical produced from biomass, and has potential applications as a versatile platform chemical, food additive, metal sequestering agent, and therapeutic agent. Marketed GA.....

Lu-Zhou Chen, Si-Ling Huang, ** Hou, Xue-** Guo… in Biotechnology for Biofuels (2020)

Article

Cell-based high-throughput screening of polysaccharide biosynthesis hosts

Valuable polysaccharides are usually produced using wild-type or metabolically-engineered host microbial strains through fermentation. These hosts act as cell factories that convert carbohydrates, such as mono...

Zi-Xu Liu, Si-Ling Huang, ** Hou, Xue-** Guo, Feng-Shan Wang… in Microbial Cell Factories (2021)

Article

Overcoming chemotherapy resistance using pH-sensitive hollow MnO₂ nanoshells that target the hypoxic tumor microenvironment of metastasized oral squamous cell carcinoma

Smart nanoscale drug delivery systems that target acidic tumor microenvironments (TME) could offer controlled release of drugs and modulate the hypoxic TME to enhance cancer therapy. The majority of previously...

Zhi-hang Zhou, Si-yuan Liang, Tong-chao Zhao, Xu-zhuo Chen… in Journal of Nanobiotechnology (2021)

Article

Boron-lead multiple bonds in the PbB₂O^– and PbB₃O₂^– clusters

Despite its electron deficiency, boron can form multiple bonds with a variety of elements. However, multiple bonds between boron and main-group metal elements are relatively rare. Here we report the observatio...

Wei-Jia Chen, Teng-Teng Chen, Qiang Chen, Hai-Gang Lu… in Communications Chemistry (2022)

Article

Large-scale preparation of polylactic acid/polyethylene glycol micro/nanofiber fabrics with aligned fibers via a post-drafting melt blown process

Polylactic acid (PLA) micro/nanofiber fabrics with good biodegradability and biocompatibility have wide applications in the medical protective field. However, the poor flexibility, high brittleness, and insuff...

Huan-Wei Sun, Heng Zhang, Qi Zhen, Si-Fan Wang, Jun-Jie Hu… in Journal of Polymer Research (2022)

Article

Application of MOF-based nanotherapeutics in light-mediated cancer diagnosis and therapy

Light-mediated nanotherapeutics have recently emerged as promising strategies to precisely control the activation of therapeutic reagents and imaging probe both in vitro and in vivo, largely ascribed to their ...

Dan Zhao, Wang Zhang, Shuang Yu, Si-Lei **a, Ya-Nan Liu… in Journal of Nanobiotechnology (2022)

Article

Engineering Escherichia coli for high-yielding 2,5-Dimethylpyrazine synthesis from L-Threonine by reconstructing metabolic pathways and enhancing cofactors regeneration

2,5-Dimethylpyrazine (2,5-DMP) is important pharmaceutical raw material and food flavoring agent. Recently, engineering microbes to produce 2,5-DMP has become an attractive alternative to chemical synthesis ap...

**n-**n Liu, Yao Wang, Jian-Hui Zhang… in Biotechnology for Biofuels and Bioproducts (2024)

Article

Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy

Recently, environmental temperature has been shown to regulate bone homeostasis. However, the mechanisms by which cold exposure affects bone mass remain unclear. In our present study, we observed that exposure...

Li-Min Lei, Fu-**ng-Zi Li, **ao Lin, Feng Xu, Su-Kang Shan… in Journal of Nanobiotechnology (2024)