10 Result(s)

Article

Silencing long non-coding RNA HOTAIR exerts anti-oncogenic effect on human acute myeloid leukemia via demethylation of HOXA5 by inhibiting Dnmt3b

As an aggressive hematological malignancy, acute myeloid leukemia (AML) remains a dismal disease with poor prognosis. Long non-coding RNAs (lncRNAs) have been widely reported to be involved in tumorigenesis of...

Si-Li Wang, Yun Huang, Rui Su, Yong-Yang Yu in Cancer Cell International (2019)

Article

A 3-circular RNA signature as a noninvasive biomarker for diagnosis of colorectal cancer

Circular RNAs (circRNAs), a novel type of noncoding RNAs, play critical roles in the initiation and progression of cancer. Emerging studies also shows that circRNAs may function as potential markers for cancer...

Dao-xiong Ye, Si-si Wang, Ying Huang, Pan Chi in Cancer Cell International (2019)

Article

CDK5RAP3 inhibits angiogenesis in gastric neuroendocrine carcinoma by modulating AKT/HIF-1α/VEGFA signaling

Angiogenesis plays critical roles in the progression and metastasis of malignant tumors. Gastric neuroendocrine carcinoma is an uncommon stomach cancer that is rich in blood vessels and exhibits highly maligna...

Jian-**an Lin, **ong-Feng Weng, **n-Sheng **e, Ning-Zi Lian… in Cancer Cell International (2019)

Article

miR-100-3p inhibits cell proliferation and induces apoptosis in human gastric cancer through targeting to BMPR2

miR-100 has been reported to closely associate with gastric cancer (GC) initiation and progression. However, the underlying mechanism of miR-100-3p in GC is still largely unclear. In this study, we intend to s...

Chun-Wei Peng, Ling-**ao Yue, Yuan-Qin Zhou, Sai Tang… in Cancer Cell International (2019)

Article

RETRACTED ARTICLE: LncRNA LBX2-AS1 promotes colorectal cancer progression and 5-fluorouracil resistance

Recent reports suggest that the long non-coding RNA LBX2 antisense RNA 1 (LBX2-AS1) acts as an important regulator in cancer progression, but its significance in colorectal cancer (CRC) remains undetermined.

Yu-Nan Ma, Yong-Gang Hong, Guan-Yu Yu, Si-yuan Jiang… in Cancer Cell International (2021)

Article

USP39 promotes malignant proliferation and angiogenesis of renal cell carcinoma by inhibiting VEGF-A_165b alternative splicing via regulating SRSF1 and SRPK1

The benefit of targeted therapy for renal cell carcinoma (RCC) is largely crippled by drug resistance. Rapid disease progression and poor prognosis occur in patients with drug resistance. New treatments demand...

**u-wu Pan, Da Xu, Wen-** Chen, Jia-xin Chen, Wei-jie Chen… in Cancer Cell International (2021)

Article

CEBPG promotes acute myeloid leukemia progression by enhancing EIF4EBP1

Acute myeloid leukemia (AML) is a myeloid neoplasm accounts for 7.6% of hematopoietic malignancies. AML is a complex disease, and understanding its pathophysiology is contributing to the improvement in the tre...

You Jiang, Shui-Yan Wu, Yan-Ling Chen, Zi-Mu Zhang… in Cancer Cell International (2021)

Article

Retraction Note: LncRNA LBX2-AS1 promotes colorectal cancer progression and 5-fluorouracil resistance

Yu-Nan Ma, Yong-Gang Hong, Guan-Yu Yu, Si-yuan Jiang… in Cancer Cell International (2023)

Article

MALAT1/ mir-1-3p mediated BRF2 expression promotes HCC progression via inhibiting the LKB1/AMPK signaling pathway

The long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been reported to play a vital role in the occurrence and development of various tumors. However, the underlying mecha...

Guang-Zhen Li, Guang-**ao Meng, Guo-Qiang Pan, **ao Zhang… in Cancer Cell International (2023)

Article

Enhancing therapeutic efficacy in luminal androgen receptor triple-negative breast cancer: exploring chidamide and enzalutamide as a promising combination strategy

Extensive exploration of the molecular subtypes of triple-negative breast cancer (TNBC) is critical for advancing precision medicine. Notably, the luminal androgen receptor (LAR) subtype has attracted attentio...

Ya-**n Zhao, Han Wang, Si-Wei Zhang, Wei-**n Zhang… in Cancer Cell International (2024)