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  1. No Access

    Article

    Z-LLY-FMK Attenuates Intestinal Apoptosis After Bile Duct Ligation in Rats

    Apoptosis is an important process in a wide variety of different biological systems. In addition to caspases, recently, calpains, another family of proteases, have been found to be involved in apoptosis of man...

    Shyr-Ming Sheen-Chen, Hsin-Tsung Ho, Hock-Liew Eng in Digestive Diseases and Sciences (2009)

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    Article

    Combination of Adult Intussusception and Intestinal Malrotation: An Unusual Presentation

    Intussusception is familiar to pediatric surgeons but is rarely encountered by general surgeons. Adult intussusception is uncommon, accounting for less than 5% of intestinal obstructions, half of which are ass...

    Ting-Min Hsieh, Shyr-Ming Sheen-Chen, Chih-Che Lin in Digestive Diseases and Sciences (2008)

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    Article

    Z-LLY-FMK Can Attenuate Hepatocyte Apoptosis After Bile Duct Ligation in Rat

    Background Cholestasis leading to retention and accumulation of toxic hydrophobic bile salts within hepatocytes may cause hepatocyte toxicity by inducing apoptosis. Calpains have been fou...

    Shyr-Ming Sheen-Chen, Hsin-Tsung Ho, Kuo-Sheng Hung… in Digestive Diseases and Sciences (2008)

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    Article

    Abdominal Carcinomatosis Attributed to Metastatic Breast Carcinoma

    A 41-year-old female suffered from epigastralgia and intermittent constipation for 10 months, and abdominal fullness and intermittent pain for 6 months, before seeking help. Double contrast barium study of the...

    Shyr-Ming Sheen-Chen, Yueh-Wei Liu, Cheuk-Kwan Sun… in Digestive Diseases and Sciences (2008)

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    Article

    Extremely Elevated CA19-9 in Acute Cholangitis

    A 68-year-old women was admitted with the chief complaints of epigastralgia with radiation to the back and jaundice. Fever and chills were also noted. The laboratory data showed alkaline phosphatase, 245 U/L (...

    Shyr-Ming Sheen-Chen, Cheuk-Kwan Sun, Yei-Wei Liu… in Digestive Diseases and Sciences (2007)

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    Article

    The Effect of Insulin-like Growth Factor-I on Hepatocyte Apoptosis After Bile Duct Ligation in Rat

    Obstructive jaundice may promote bacterial overgrowth and altered intestinal barrier function, with resultant increased translocation of endotoxin to the liver, amd thus may potentiate the phenomenon of hepato...

    Shyr-Ming Sheen-Chen, Hsin-Tsung Ho, Lu Chia-Pei… in Digestive Diseases and Sciences (2006)

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    Article

    Obstructive Jaundice Alters LFA-1α Expression in Rat Small Intestine

    Translocation of bacteria and endotoxtin has long been documented in obstructive jaundice, and altered intestinal barrier function is considered to be one of the important mechanisms for this phenomenon. The r...

    Shyr-Ming Sheen-Chen, Han-Shiang Chen, Hsin-Tsung Ho… in Digestive Diseases and Sciences (2003)

  8. No Access

    Article

    Progesterone Receptor in Patients with Hepatolithiasis

    Altered gallbladder motility by progesterone has been recognized as an important factor in the development of gallstones. There are two types of hepatolithiasis, that occurs de novo in the intrahepatic ducts with...

    Shyr-Ming Sheen-Chen, Hsin-Tsung Ho, Wei-Jen Chen… in Digestive Diseases and Sciences (2001)