![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open Accessc-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities
Tumor necrosis factor (TNF) and Toll-like receptor (TLR)3/TLR4 activation trigger necroptotic cell death through downstream signaling complex containing receptor-interacting protein kinase 1 (RIPK1), RIPK3, an...
-
Article
Open AccessStructural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies
Neutralizing monoclonal antibodies (nAbs) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represent promising candidates for clinical intervention against coronavirus disease 2019 (COVID-19). W...
-
Article
Open AccessLoss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2
-
Article
Open AccessMutant kri1l causes abnormal retinal development via cell cycle arrest and apoptosis induction
Damage to the ribosome or an imbalance in protein biosynthesis can lead to some human diseases, such as diabetic retinopathy (DR) and other eye diseases. Here, we reported that the kri1l gene was responsible for ...