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  1. Article

    Open Access

    Clinical prediction models for the early diagnosis of obstructive sleep apnea in stroke patients: a systematic review

    Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repetitive cessation or reduction in airflow during sleep. Stroke patients have a higher risk of OSA, which can worsen their cognitive ...

    Hualu Yang, Shuya Lu, Lin Yang in Systematic Reviews (2024)

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  2. No Access

    Article

    Ammonia detoxification promotes CD8+ T cell memory development by urea and citrulline cycles

    Amino acid metabolism is essential for cell survival, while the byproduct ammonia is toxic and can injure cellular longevity. Here we show that CD8+ memory T (TM) cells mobilize the carbamoyl phosphate (CP) metab...

    Ke Tang, Huafeng Zhang, **ghui Deng, Dianheng Wang, Shichuan Liu… in Nature Immunology (2023)

  3. No Access

    Article

    Role of endoplasmic reticulum stress in apoptosis induced by HK2 inhibitor and its potential as a new drug combination strategy

    Compared with normal cells, tumor cells mainly obtain energy through aerobic glycolysis. Hexokinase 2 (HK2) plays a key role in the regulation of tumor cell aerobic glycolysis, and targeting HK2 has become a n...

    Jiateng Zhong, Shuya Lu, **aoling Jia, Qian Li, Lei Liu… in Cell Stress and Chaperones (2022)

  4. Article

    Open Access

    Reporting quality evaluation of the stroke clinical practice guidelines: a systematic review

    To analyze the effectiveness and quality of stroke clinical practice guidelines (CPGs) published in recent years in order to guide future guideline developers to develop better guidelines.

    Shuya Lu, Xufei Luo, **aojia Ni, Haoxuan Li, Miaomiao Meng… in Systematic Reviews (2021)

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