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    PABPC1 silencing inhibits pancreatic cancer cell proliferation and EMT, and induces apoptosis via PI3K/AKT pathway

    Pancreatic cancer is difficult to manage owing to the challenges involved in its treatment and nursing. This study aimed to clarify the roles and mechanisms of action of Poly (A)-binding protein cytoplasmic 1 ...

    Changren Zhu, Cuimei Wang, **aodong Wang, Shuangshuang Dong, Qing Xu in Cytotechnology (2024)

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    miR-92a-3p promotes pulmonary fibrosis progression by regulating KLF2-mediated endothelial-to-mesenchymal transition

    Pulmonary fibrosis (PF) is a chronic lung disease that has a poor prognosis and a serious impact on the quality of life of patients. Here, we investigated the potential role of miR-92a-3p in PF. The mRNA level...

    Sisi Pang, Bo Chen, Yan Li, Shuangshuang Wu, Lei Chen in Cytotechnology (2024)

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    Article

    Therapeutic “Tool” in Reconstruction and Regeneration of Tissue Engineering for Osteochondral Repair

    Repairing osteochondral defects to restore joint function is a major challenge in regenerative medicine. However, with recent advances in tissue engineering, the development of potential treatments is promisin...

    Xueyan Hu, Jie Xu, Wenfang Li, Liying Li in Applied Biochemistry and Biotechnology (2020)

  4. Article

    In Vitro Fabrication and Biocompatibility Assay of a Biomimetic Osteoblastic Niche

    A novel HAp-CS/Gel biomimetic osteoblastic niche was fabricated by freeze-drying, and its mechanical strength and biocompatibility were characterized. HAp-CS/Gel scaffolds in various ratios of 100:5, 100:10, a...

    Kedong Song, Qian Kong, Liying Li, Yiwei Wang in Applied Biochemistry and Biotechnology (2019)

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    Article

    Harvesting Microalgae with Different Sources of Starch-Based Cationic Flocculants

    In this study, starches obtained from wheat, potato, and corn were used to synthesize cationic starches (CS), and the flocculation efficiency of these materials was tested with Chlorella pyrenoidosa and Botryococ...

    Chengrong Peng, Shuangshuang Li, Jiaoli Zheng in Applied Biochemistry and Biotechnology (2017)

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    Article

    Protein-Coated Microcrystals from Candida rugosa Lipase: Its Immobilization, Characterization, and Application in Resolution of Racemic Ibuprofen

    In this study, an economical heterogeneous biocatalyst, protein-coated microcrystals (PCMCs), was prepared from a commercial Candida rugosa lipase (CRL) and used for catalyzing esterification of (R, S)-ibuprofen ...

    Shuangshuang Huang, **ang Li, Li Xu, Caixia Ke in Applied Biochemistry and Biotechnology (2015)

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    Article

    DNA Damage and Effects on Antioxidative Enzymes in Earthworm (Eisenia fetida) Induced by Flumorph

    Flumorph is an Oomycete fungicide, which is used extensively as an effective fungicide in vegetables and fruits, but little is known about its effect on nontarget soil organisms. In the present study, biochemi...

    **angyu Cao, Chao Yang, Jianli Liu, **ujuan Hui in Applied Biochemistry and Biotechnology (2014)