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Article
Effect of coffee, tea and alcohol intake on circulating inflammatory cytokines: a two sample-Mendelian randomization study
Despite the abundance of research examining the effects of coffee, tea, and alcohol on inflammatory diseases, there is a notable absence of conclusive evidence regarding their direct causal influence on circul...
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Article
Preparation of water-soluble tantalum nanoparticles and their radiosensitization application
Radiation therapy (RT) that utilizes high dose of ionizing radiation to kill tumor cells is a common cancer treatment method. However, the effectiveness of RT is limited by the tolerance of normal tissue surro...
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Article
Research on the effect and mechanism of composite phase change materials inhibiting low-temperature oxidation of coal
Coal spontaneous combustion often occurs in hidden areas and is one of the main disasters in mines. The process of coal spontaneous combustion can be effectively blocked by adding inhibitors. A composite phase...
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Article
Open AccessBI-2865, a pan-KRAS inhibitor, reverses the P-glycoprotein induced multidrug resistance in vitro and in vivo
Multidrug resistance (MDR) limits successful cancer chemotherapy. P-glycoprotein (P-gp), BCRP and MRP1 are the key triggers of MDR. Unfortunately, no MDR modulator was approved by FDA to date. Here, we will in...
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Article
Non-targeted mass spectrometry and feature-based molecular networking for determination of branched fatty acid esters of hydroxy fatty acids in milk
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) represent trace lipids with significant natural biological functions. While exogenous FAHFAs have been extensively studied, research on FAHFAs in milk...
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Article
Acute pancreatitis and metabolic syndrome: genetic correlations and causal associations
Although there is a definite correlation between the Metabolic Syndrome (MetS) and Acute Pancreatitis (AP), cause is yet unknown. The current work combined linkage disequilibrium score (LDSC) regression and Me...
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Article
Correction: An Emotional Skills Intervention for Elementary Children with Autism in China: A Pilot Study
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Article
Effect of Nitrogen on Solidification Structure and Microsegregation of Electroslag Remelted 7Cr13 Steel
The macrostructure, microstructure and alloying element microsegregation of electroslag remelted (ESR) 7Cr13 steel with different nitrogen contents (0.043, 0.084, 0.164 pct) were studied. The maximum solubilit...
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Article
Block motion, slip rates, and earthquake hazard assessment of boundary faults in the Sichuan–Yunnan region, China
Quantitative analysis of the slip rate of active faults and their seismic parameters is important for seismic hazard analysis. In this study, we first construct an elastic block model to obtain the slip rate o...
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Article
Open AccessMechanistic insight into the competition between interfacial and bulk reactions in microdroplets through N2O5 ammonolysis and hydrolysis
Reactive uptake of dinitrogen pentaoxide (N2O5) into aqueous aerosols is a major loss channel for NOx in the troposphere; however, a quantitative understanding of the uptake mechanism is lacking. Herein, a comput...
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Article
A bibliometric analysis of molybdenum-based nanomaterials in the biomedical field
Molybdenum (Mo)-based nanomaterials have been widely used in biomedical fields due to their various nanostructures and unique physical/chemical properties. Although various reviews have described the developme...
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Article
Effect of Quenching and Tempering Processes on Sharpness of Knives Made from 6Cr13 High-Carbon Martensitic Stainless Steel
In the present work, the effect of quenching and tempering processes on the sharpness performance of 6Cr13 high-carbon martensitic stainless steel knives was investigated. The results show that the sharp persi...
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Chapter and Conference Paper
Precipitation and Evolutionary Behavior of Eutectic Carbides in Electroslag Remelted 7Cr13N Steel
evolutionary behavior in were investigated and compared with 8Cr13MoV steel. The results showed that the eutectic at the center and edge of 7Cr13N ingot was reduced by 26.8% and 67.0% compared with 8C...
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Chapter and Conference Paper
Efficient Video Deblurring Guided by Motion Magnitude and Convolutional Block Attention Module
Video deblurring is a pivotal task in the fields of low-level vision and graphics, aiming to restore clear videos from blurry sequences. The traditional approaches usually involve restoring the blurry middle f...
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Article
Open AccessApplication of the ‘online assessment + FOBT at home’ to improve participation and the efficacy of opportunistic screening for colorectal cancer: a retrospective cohort study
Colorectal cancer (CRC) screening faces two major challenges: insufficient screening coverage and poor adherence. A smartphone applet named “Early Screening Assistant (ESA)” was developed to create an online r...
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Article
Magnetic phase transition and continuous spin switching in a high-entropy orthoferrite single crystal
Rare-earth orthoferrite REFeO3 (where RE is a rare-earth ion) is gaining interest. We created a high-entropy orthoferrite (Tm0.2Nd0.2Dy0.2Y0.2Yb0.2) FeO3 (HEOR) by do** five RE ions in equimolar ratios and grew...
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Article
Joint adjustment of strain rate fields and its application in shallow seismicity forecast in the Sichuan-Yunnan region, China
Calculation methods for large-scale strain rate fields from GNSS horizontal velocity can be divided into two types, namely mathematical and physical methods, which reflect different characteristics of the stra...
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Article
Open AccessFusobacterium nucleatum upregulates MMP7 to promote metastasis-related characteristics of colorectal cancer cell via activating MAPK(JNK)-AP1 axis
Colorectal cancer (CRC) is the third most common malignant tumor. Fusobacterium nucleatum (F. nucleatum) is overabundant in CRC and associated with metastasis, but the role of F. nucleatum in CRC cell migration a...
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Article
Open AccessImproved survival outcome with not-delayed radiotherapy and immediate PD-1/PD-L1 inhibitor for non-small-cell lung cancer patients with brain metastases
To investigate the impact of radiotherapy (RT) and immune checkpoint inhibitor (ICI) sequence on the survival outcome in NSCLC patients with brain metastasis, and decide the best time to initiate RT.
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Article
Open AccessFocal adhesion kinase: from biological functions to therapeutic strategies
Focal adhesion kinase (FAK), a nonreceptor cytoplasmic tyrosine kinase, is a vital participant in primary cellular functions, such as proliferation, survival, migration, and invasion. In addition, FAK regulate...
