1,462 Result(s)
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Shu-**an Xu
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Article
ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the olfactory bulb (OB) ...
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Open AccessChromosome-level genome assembly of an oligophagous leaf beetle Ophraella communa (Coleoptera: Chrysomelidae)
The leaf beetle Ophraella communa LeSage (Coleoptera: Chrysomelidae) is an effective biological control agent of the common ragweed. Here, we assembled a chromosome-level genome of the O. communa by combining Ill...
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Research progress and development tendency on storage mechanism of multi-principal element alloys for hydrogen/tritium storage
Sustainable clean energy is gradually replacing traditional fossil energy sources in important industrial applications and is placing higher demands on the technologies of energy storage and transportation. Th...
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Boosting Stability and Efficiency: Defect-Rich Pd/NC Catalysts for Nitric Acid Reduction to Methyl Nitrite
Reduction of nitric acid reaction (2NO + HNO3 + 3CH3OH → 3CH3ONO + 2H2O) can convert by-product nitric acid into raw material methyl nitrite in the coal to ethylene glycol (CTEG) technology. This not only realize...
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Decreasing mitochondrial fission ameliorates HIF-1α-dependent pathological retinal angiogenesis
Angiogenesis plays a critical role in many pathological processes, including irreversible blindness in eye diseases such as retinopathy of prematurity. Endothelial mitochondria are dynamic organelles that unde...
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Estimating the Mechanical Properties of Rocks and Rock Masses Based on Mineral Micromechanics Testing
Estimation of rock uniaxial compressive strength and elastic modulus from mineral micromehanical properties.
Upscaling tech...
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Molecular docking-aided AIEgen design: concept, synthesis and applications
Aggregate-induced emission luminogens (AIEgens) have been widely used in biological imaging, chemical sensing, and disease treatments. The rational design and construction of AIEgens have received considerable...
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High-resolution remote thermometry based on Bi3+-doped 0D zinc halide hybrids
Develo** highly sensitive optical thermometers is of great significance due to their capability to enable remote and non-contact temperature measurements, rendering them highly applicable in diverse and hars...
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AI for organic and polymer synthesis
Recent years have witnessed the transformative impact from the integration of artificial intelligence with organic and polymer synthesis. This synergy offers innovative and intelligent solutions to a range of ...
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Open AccessDeep learning model for the prediction of all-cause mortality among long term care people in China: a prospective cohort study
This study aimed to develop a deep learning model to predict the risk stratification of all-cause death for older people with disability, providing guidance for long-term care plans. Based on the government-le...
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Open AccessA case study of lean digital transformation through robotic process automation in healthcare
Under Taiwan's National Health Insurance (NHI) system, it's crucial for all healthcare providers to accurately submit medical expense claims to the National Health Insurance Administration (NHIA) to avoid inco...
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Application of modified cerium dioxide for photocatalytic air pollution purification
Cerium dioxide (CeO2) is a significant rare earth oxide with the merits of rich oxygen defects, specific 4f15d1 orbitals, and superior oxygen storage-release capacity in Ce4+/Ce3+ reversibility pairs, and has bee...
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Regulations of m6A and other RNA modifications and their roles in cancer
RNA modification is an essential component of the epitranscriptome, regulating RNA metabolism and cellular functions. Several types of RNA modifications have been identified to date; they include N6-methyladenosi...
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Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
The impairment of blood-brain barrier (BBB) integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy. There is no approved drug in th...
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Open AccessAMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...
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Open AccessTripartite motif 8 promotes the progression of hepatocellular carcinoma via mediating ubiquitination of HNF1α
Tripartite motif 8 (TRIM8) is an E3 ligase that plays dual roles in various tumor types. The biological effects and underlying mechanism of TRIM8 in hepatocellular carcinoma (HCC) remain unknown. Hepatocyte nu...
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Open AccessSerum selenium and fasting blood glucose: a cross-sectional study in women of different menopause status
This cross-sectional study aims to explore whether there exists an interaction between selenium and menopause concerning type 2 diabetes (T2D) prevalence and its related indicators such as fasting blood glucos...
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Open AccessSingle-crystalline hole-transporting layers for efficient and stable organic light-emitting devices
Efficient charge-carrier injection and transport in organic light-emitting devices (OLEDs) are essential to simultaneously achieving their high efficiency and long-term stability. However, the charge-transport...
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Efficient socket-based data transmission method and implementation in deep learning
The deep learning algorithm, which has been increasingly applied in the field of petroleum geophysical prospecting, has achieved good results in improving efficiency and accuracy based on test applications. To...
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Precipitation evolution and properties of Cu-15Ni-8Sn alloys via Al microalloying during ageing
Studies have shown that microalloying Cu–Ni–Sn alloys using Al inhibits discontinuous precipitation reactions; however, the mechanism has not been investigated yet. Thus, this study explored the properties and...
