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Article
Application of a Novel Mitral Valvuloplasty Strategy in Children with Mitral Regurgitation
To retrospectively analyze the clinical efficacy of an innovative mitral valvuloplasty strategy in the treatment of mitral regurgitation in children. From January 2018 to December 2022, 140 patients undergoing...
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Article
Clinical Outcomes, Predictors, and Surgical Management of Infracardiac Total Anomalous Pulmonary Venous Connection
This study sought to find the risk factors of postoperative pulmonary venous obstruction (PVO), PVO-related reintervention, and postoperative mortality, determine the relationship between pulmonary venous conf...
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Article
Long-Term Outcomes of Surgical Repair of Supracardiac Total Anomalous Pulmonary Venous Connection
The conventional surgery (CS) of supracardiac total anomalous pulmonary venous connection (TAPVC) is not always effective particularly in the setting of complex anatomy such as the mixed variety of TAPVC. This...
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Article
Long-Term Outcomes of Individualized Repair in Patients with Supravalvular Aortic Stenosis
Various surgical techniques have been introduced to treat supravalvular aortic stenosis (SVAS). However, there is no consensus on the optimal approach. This study aimed to analyze the outcomes of surgical trea...
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Article
Open AccessMelatonin alleviates chronic stress-induced hippocampal microglia pyroptosis and subsequent depression-like behaviors by inhibiting Cathepsin B/NLRP3 signaling pathway in rats
Melatonin improves chronic stress-induced hippocampal damage and depression-like behaviors, but the mechanism needs further study. This study was to explore the mechanism of melatonin inhibiting microglia pyro...
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Article
Open AccessConstruction of recombinant fluorescent LSDV for high-throughput screening of antiviral drugs
Lumpy skin disease virus (LSDV) infection is a major socio-economic issue that seriously threatens the global cattle-farming industry. Here, a recombinant virus LSDV-ΔTK/EGFP, expressing enhanced green fluores...
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Article
Predictive Value of Myocardial Markers for Early Postoperative Mortality in Children with Congenital Heart Disease
To investigate the influencing factors of postoperative creatine kinase-MB (CK-MB) elevation in children with congenital heart disease and its peak value in predicting early postoperative mortality. The clinic...
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Article
Geochemistry of the Early Cretaceous saline lacustrine shales on the Lingshan Island, East China: implications for provenance, tectonic setting, and paleoweathering
Early Cretaceous saline lacustrine black shales in the Fajiaying Formation were deposited under hothouse conditions and have a complex structure and history of sedimentary evolution. In this study, integrated ...
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Article
Open AccessCongenital heart diseases with airway stenosis: a predictive nomogram to risk-stratify patients without airway intervention
This study focused on congenital heart disease (CHD) patients complicated with airway stenosis (AS) without airway intervention and aimed to identify the patients with potential risks.
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Article
Open AccessDevelopment and application of a dual ERA method for the detection of Feline Calicivirus and Feline Herpesvirus Type I
Feline calicivirus (FCV) and feline herpesvirus type I (FHV-1) are the most common viral pathogens responsible for cat respiratory diseases, and coinfection with these two pathogens is often found. In veterina...
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Article
Open AccessEstablishment and characterization of a HER2-enriched canine mammary cancerous myoepithelial cell line
Canine mammary tumors (CMTs) have a poor prognosis, along with tumor recurrence and metastasis. Cell lines are vital in vitro models for CMT research. Many CMT epithelial cell lines were reported. However, can...
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Article
Open AccessMap** the early life gut microbiome in neonates with critical congenital heart disease: multiomics insights and implications for host metabolic and immunological health
The early life gut microbiome is crucial in maintaining host metabolic and immune homeostasis. Though neonates with critical congenital heart disease (CCHD) are at substantial risks of malnutrition and immune ...
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Article
Open AccessMolecular characterization and antiviral effects of canine interferon regulatory factor 1 (CaIRF1)
Interferon regulatory factor 1 (IRF1) is an important transcription factor that activates the type I interferon (IFN-I) response and plays a vital role in the antiviral immune response. Although IRF1 has been ...
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Article
Application of sulfur isotopes for analysing the sedimentary environment of evaporite in low-altitude intermountain basins: a case study on the Kumishi basin, Northwest China
The formation environment of continental evaporite—particularly the sedimentary environment closely related to continental evaporite deposits—has received significant research attention for several years. From...
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Article
First identification and genomic characterization of equine hepacivirus subtype 2 in China
Equine hepacivirus (EqHV) is a newly discovered hepatitis C virus–like virus that can infect equines. EqHV strains circulating worldwide have been classified into subtypes 1-3. In previous studies, we detected...
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Article
Beagle Dogs Have Low Susceptibility to Florida Clade 2 H3N8 Equine Avian Influenza
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Article
Transposition of the Great Arteries, Ventricular Septal Defect, and Pulmonary Stenosis: Modified REV versus Rastelli
The objective of this study was to evaluate and compare the results of the modified réparation à l’ètage ventriculaire (REV) and the Rastelli operation for the treatment of transposition of the great arteries ...
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Article
Open AccessEarly extubation is associated with improved outcomes after complete surgical repair of pulmonary atresia with ventricular septal defect and hypoplastic pulmonary arteries in pediatric patients
The aim of this study was to investigate the impact of an early extubation strategy on outcomes following complete repair of pulmonary atresia, ventricular septal defect, and hypoplastic pulmonary artery.
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Article
Impact of Annulus-Sparing on Surgical Adequacy of Pulmonary Valve in Complete Repair of Tetralogy of Fallot with Right Ventricular Outflow Tract Incision
Today, strategy of repair remains controversial and rare analyses on annular integrity associated with outcomes in complete repair by RVOT incision were performed in a large TOF cohort in China. This is a retr...
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Article
Clinical Outcome of Patients with Transposition of the Great Arteries and Intramural Coronary Artery
To review the early and intermediate outcomes of patients with transposition of the great arteries (TGA) and intramural coronary artery (IMCA) who underwent arterial switch operation (ASO) at our center. Among...
