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  1. Article

    Open Access

    Methylation patterns in serum DNA for early identification of disseminated breast cancer

    Monitoring treatment and early detection of fatal breast cancer (BC) remains a major unmet need. Aberrant circulating DNA methylation (DNAme) patterns are likely to provide a highly specific cancer signal. We ...

    Martin Widschwendter, Iona Evans, Allison Jones, Shohreh Ghazali in Genome Medicine (2017)

  2. Article

    Open Access

    The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer

    Despite a myriad of attempts in the last three decades to diagnose ovarian cancer (OC) earlier, this clinical aim still remains a significant challenge. Aberrant methylation patterns of linked CpGs analyzed in...

    Martin Widschwendter, Michal Zikan, Benjamin Wahl, Harri Lempiäinen in Genome Medicine (2017)