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    Chapter

    Etiology, Pathogenesis, and Genetics of Parkinson’s Disease

    Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease. Recent scientific interest has been focused on the molecular mechanism of nigral neuronal death and how t...

    Yoshikuni Mizuno, Nobutaka Hattori in Map** the Progress of Alzheimer’s and Pa… (2002)

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    Chapter

    Ubiquitin-Proteasome Pathway is a Key to Understanding of Nigral Degeneration in Autosomal Recessive Juvenile Parkinson’s Disease

    In most patients with Parkinson’s disease (PD), the contribution of genetic and environmental factors remains to be elucidated. The importance of genes in PD was controversial for many years. It has become cle...

    Nobutaka Hattori, Shuichi Asakawa in Map** the Progress of Alzheimer’s and Pa… (2002)