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Article
Maternal phthalate exposure and BMI trajectory in children—an 18-year birth cohort follow-up study
Obesity is a major health concern worldwide. Previous studies have suggested that phthalate plasticizers are obesogens. However, the relationship between early-life phthalate exposure and long-term obesity dev...
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Article
Open AccessPreoperative assessment of bone density for dental implantation: a comparative study of three different ROI methods
Dental cone beam computed tomography (CBCT) is commonly used to evaluate cancellous bone density before dental implant surgery. However, to our knowledge, no measurement approach has been standardized yet. Thi...
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Article
The effect of craniocervical flexion and neck endurance exercises plus pulmonary rehabilitation on pulmonary function in spinal cord injury: a pilot single-blinded randomised controlled trial
Randomised controlled trial with computerised allocation, assessor blinding and intention-to-treat analysis.
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Article
Open AccessAPOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
Several genetic risk factors for Alzheimer’s disease implicate genes involved in lipid metabolism and many of these lipid genes are highly expressed in glial cells1. However, the relationship between lipid metabo...
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Article
Open AccessGenetic drivers of heterogeneity in type 2 diabetes pathophysiology
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic c...
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Article
Open AccessThe influence of chronic renal insufficiency on multi-therapeutic modalities for breast cancer: a single-center experience
Due to the presence of other comorbidities and multi-therapeutic modalities in breast cancer, renally cleared chemotherapeutic regimens may cause nephrotoxicity. The aim of this retrospective study is to compa...
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Article
Open AccessNovel lissencephaly-associated NDEL1 variant reveals distinct roles of NDE1 and NDEL1 in nucleokinesis and human cortical malformations
The development of the cerebral cortex involves a series of dynamic events, including cell proliferation and migration, which rely on the motor protein dynein and its regulators NDE1 and NDEL1. While the loss ...
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Chapter and Conference Paper
Exploring the Relationship Between Generation Z's Beauty Experience and Brand Loyalty: A Comprehensive Study in the Experience Economy Era
In the era of the experience-driven economy, consumer demands are evolving towards highly personalized and unique service experiences. Concurrently, demographic shifts, particularly the rise of Generation Z, f...
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Article
Open AccessEndosomal Arl4A attenuates EGFR degradation by binding to the ESCRT-II component VPS36
Ligand-induced epidermal growth factor receptor (EGFR) endocytosis followed by endosomal EGFR signaling and lysosomal degradation plays important roles in controlling multiple biological processes. ADP-ribosyl...
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Article
Open AccessIncreased risk of chronic fatigue syndrome following infection: a 17-year population-based cohort study
Previous serological studies have indicated an association between viruses and atypical pathogens and Chronic Fatigue Syndrome (CFS). This study aims to investigate the correlation between infections from comm...
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Article
Open AccessPrediction of incidence of neurological disorders in HIV-infected persons in Taiwan: a nested case–control study
Neurological disorders are still prevalent in HIV-infected people. We aimed to determine the prevalence of neurological disorders and identify their risk factors in HIV-infected persons in Taiwan.
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Article
High-density characterization of the sinus rhythm: a new functional substrate map of scar-related atrial tachycardia
Reentrant atrial tachycardias (ATs) utilize critical isthmus (CI) for the maintenance of the circuit. The electrophysiological characteristics and clinical implications of the targeted CI regions of reentrant ...
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Article
Association of Ferroptosis with Severity and Outcomes in Acute Ischemic Stroke Patients Undergoing Endovascular Thrombectomy: A Case-control Study
Ferroptosis, an iron-dependent form of cell death, is characterized by intracellular accumulation of iron and reactive oxygen species-induced lipid peroxidation. Animal experiments have shown the important rol...
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Article
Open AccessNeural mechanism facilitating PM2.5-related cardiac arrhythmias through cardiovascular autonomic and calcium dysregulation in a rat model
Particulate matter < 2.5 μm (PM2.5) exposure is associated with increased arrhythmia events and cardiovascular mortality, but the detailed mechanism remained elusive. In the current study, we aimed to investig...
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Article
Open AccessAssessment of factors influencing physicians’ intention to prescribe transfusion using the theory of planned behavior
Blood shortage is a persistent problem affecting Taiwan’s health-care system. The theory of planned behavior (TPB) has been commonly used in studies of health advocacy. The purpose of this study was to develop...
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Article
A comparison study between the use of single-point versus areal-mean rainfall values from a high-resolution model when verified against satellite retrievals for three typhoons hitting the Philippines
In this study, effects of using areal-mean instead of single-point output values from a cloud-resolving model to verify its quantitative precipitation forecasts (QPFs) in terms of the categorical 2 × 2 matrix ...
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Article
Open AccessReconstruction of interactions in the ProtoDUNE-SP detector with Pandora
The Pandora Software Development Kit and algorithm libraries provide pattern-recognition logic essential to the reconstruction of particle interactions in liquid argon time projection chamber detectors. Pandor...
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Article
Open AccessThe Skeletal Oncology Research Group Machine Learning Algorithm (SORG-MLA) for predicting prolonged postoperative opioid prescription after total knee arthroplasty: an international validation study using 3,495 patients from a Taiwanese cohort
Preoperative prediction of prolonged postoperative opioid use (PPOU) after total knee arthroplasty (TKA) could identify high-risk patients for increased surveillance. The Skeletal Oncology Research Group machi...
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Article
Open AccessGenome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study o...
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Article
Open AccessNew classification for bone type at dental implant sites: a dental computed tomography study
This study proposed a new classification method of bone quantity and quality at the dental implant site using cone-beam computed tomography (CBCT) image analysis, classifying cortical and cancellous bones sepa...
