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    Article

    Tumorigenicity of interleukin-2 (IL-2)-cDNA-transfected L1210 lymphoma and its in vivo variants is modulated by changes in IL-2 expression; potential therapeutic implications

    To study parameters that affect the tumorigenicity of L1210 lymphoma we have analyzed the structure of MHC class I antigens of this tumor. In addition this tumor was transfected with interleukin-2 (IL-2) cDNA ...

    Prabir K. Chakravarty, Hiroshi Fuji in Cancer Immunology, Immunotherapy (1992)

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    Article

    Interleukin-2 secretion by KHT sarcoma cells leads to loss of their vaccine potential

     We have investigated the effect of interleukin-2 (IL-2) secretion by KHT sarcoma cells upon their vaccine potential in syngeneic C3Hf/He mice. Parental KHT tumor cells were transfected with the plasmid pBCMG-...

    Shih-chung Hsu, Dorothy Glaves, A. K. Sood in Cancer Immunology, Immunotherapy (1997)