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4 Result(s)

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  1. Article

    Open Access

    Surgical treatment improves overall survival of hepatocellular carcinoma with extrahepatic metastases after conversion therapy: a multicenter retrospective study

    Systemic therapy is typically the primary treatment choice for hepatocellular carcinoma (HCC) patients with extrahepatic metastases. Some patients may achieve partial response (PR) or complete response (CR) wi...

    **aoshi Zhang, **aodong Zhu, Jianhong Zhong, Yang Zhao, **aoyun Zhang… in Scientific Reports (2024)

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  2. Article

    Open Access

    Cellular senescence affects energy metabolism, immune infiltration and immunotherapeutic response in hepatocellular carcinoma

    Aging is an inevitable consequence of life, characterized by a progressive decline in tissue and organ function and an increased risk of death. There is growing evidence that aging is closely related to tumor ...

    Biao Gao, Yafei Wang, Shichun Lu in Scientific Reports (2023)

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  3. Article

    Open Access

    A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) represents a paradigm of the relation between tumor microenvironment (TME) and tumor development. Here, we generate a single-cell atlas of the multicellular ecosystem of HCC from...

    Yiming Lu, Aiqing Yang, Cheng Quan, Yingwei Pan, Haoyun Zhang… in Nature Communications (2022)

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  4. No Access

    Article

    Chemical reprogramming of human somatic cells to pluripotent stem cells

    Cellular reprogramming can manipulate the identity of cells to generate the desired cell types1–3. The use of cell intrinsic components, including oocyte cytoplasm and transcription factors, can enforce somatic c...

    **gyang Guan, Guan Wang, **lin Wang, Zhengyuan Zhang, Yao Fu, Lin Cheng… in Nature (2022)