7 Result(s)

Article

Construction and validation of a novel signature based on epithelial-mesenchymal transition–related genes to predict prognosis and immunotherapy response in hepatocellular carcinoma by comprehensive analysis of the tumor microenvironment

Immunotherapy has yielded encouraging results in the treatment of advanced hepatocellular carcinoma (HCC). However, the relationship between epithelial-mesenchymal transition (EMT) and immunotherapy for HCC ha...

Biao Gao, Yafei Wang, Shichun Lu in Functional & Integrative Genomics (2022)

Article

Generation of human hepatocytes from extended pluripotent stem cells

Qiming Wang, Da Sun, Zhen Liang, Junyi Wang, **nxing Zhong, Yulin Lyu… in Cell Research (2020)

Article

Hepatic spheroids derived from human induced pluripotent stem cells in bio-artificial liver rescue porcine acute liver failure

Sitong Chen, **glin Wang, Haozhen Ren, Yinan Liu, Chengang **ang… in Cell Research (2020)

Article

A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts

Terminally differentiated cells can be generated by lineage reprogramming, which is, however, hindered by incomplete conversion with residual initial cell identity and partial functionality. Here, we demonstra...

Bingqing **e, Da Sun, Yuanyuan Du, Jun Jia, Shicheng Sun, Jun Xu… in Cell Research (2019)

Article

Promotion of the efficient metabolic maturation of human pluripotent stem cell-derived hepatocytes by correcting specification defects

Dongxin Zhao, Song Chen, Shuguang Duo, Chengang **ang, Jun Jia, Mina Guo… in Cell Research (2013)

Article

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells

Human induced pluripotent stem (iPS) cells are similar to embryonic stem (ES) cells, and can proliferate intensively and differentiate into a variety of cell types. However, the hepatic differentiation of huma...

Zhihua Song, Jun Cai, Yanxia Liu, Dongxin Zhao, Jun Yong, Shuguang Duo… in Cell Research (2009)