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  1. Article

    Immunogenicity and protective efficacy of a DNA vaccine inducing optimal expression of the SARS-CoV-2 S gene in hACE2 mice

    The wide spread of coronavirus disease 2019 (COVID-19) has significantly threatened public health. Human herd immunity induced by vaccination is essential to fight the epidemic. Therefore, highly immunogenic a...

    Zhuo-xin Li, Sheng Feng, He Zhang, **n-yu Zhuang, Chao Shang… in Archives of Virology (2022)

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    Overexpression of the PLK4 Gene as a Novel Strategy for the Treatment of Autosomal Recessive Microcephaly by Improving Centrosomal Dysfunction

    Autosomal recessive microcephaly and chorioretinopathy (MCCRP) is a neurodevelopmental disorder characterized by delayed psychomotor development, growth retardation with dwarfism, and ocular abnormalities, and...

    Ya-Song Xu, Zhi-Ying Su, Li Sun, **ao-Mei Yang… in Journal of Molecular Neuroscience (2021)