![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
2,477 Result(s)
-
Article
Accelerated learning and co-optimization of elastocaloric effect and stress hysteresis of elastocaloric alloys
The development of high-performance advanced elastocaloric alloys is crucial for the implementation of elastocaloric refrigeration. Here, we present a machine learning (ML) framework to accelerate the developm...
-
Article
Systematic study of the synthesis of heavy and superheavy nuclei in 48Ca-induced fusion-evaporation reactions
We systematically studied the evaporation residue cross sections of \(^{48}\hbox {Ca}\) ...
-
Article
Highly stable strain sensor using rGO decorated with multi-component alloy nanoparticles for human motion monitoring
Wearable, flexible devices have garnered widespread attention in the realm of human motion and life activity detection. Currently, the development of simple, green, and easily scalable methods for fabricating ...
-
Article
Open AccessTargeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis
Neuropilin-1 (NRP1), a co-receptor for various cytokines, including TGF-β, has been identified as a potential therapeutic target for fibrosis. However, its role and mechanism in renal fibrosis remains elusive....
-
Article
Open AccessAssessment of the influence of levees along Yangtze River on Oncomelania hupensis, the intermediate host of Schistosoma japonicum
Oncomelania hupensis is the exclusive intermediate host of Schistosoma japonicum in China. Snail control is an essential component of schistosomiasis elimination programme. With 70 years of continuous efforts, th...
-
Article
Open AccessPhase separation of RNF214 promotes the progression of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, and the expression and function of an uncharacterized protein RNF214 in HCC are still unknown. Phase separation has recently been obse...
-
Article
Open AccessEAF2 Downregulation Recruits Tumor-associated Macrophages in Prostate Cancer through Upregulation of MIF
The role of tumor inflammatory microenvironment in the advancement of cancer, particularly prostate cancer, is widely acknowledged. ELL-associated factor 2 (EAF2), a tumor suppressor that has been identified i...
-
Article
A novel 3D nitrogen-doped porous carbon supported Fe-Cu bimetallic nanoparticles composite derived from lignin: an efficient peroxymonosulfate activator for naphthalene degradation
A novel 3D nitrogen-doped porous carbon supported Fe-Cu bimetallic nanoparticles composite (Fe-Cu-N-PC) was prepared via direct pyrolysis by employing black liquor lignin as a main precursor, and it was utiliz...
-
Article
Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
-
Article
Clinical prognostic value of different NPM1 mutations in acute myeloid leukemia patients
Background: Acute myeloid leukemia (AML) patients with various nucleophosmin 1 (NPM1) mutations are controversial in the prognosis. This study aimed to investigate the prognosis of patie...
-
Article
The clinical significance and prognostic value of serum beta-2 microglobulin in adult lymphoma-associated hemophagocytic lymphohistiocytosis: a multicenter analysis of 326 patients
To investigate the prognostic impact of serum beta-2 microglobulin (B2M) in adult lymphoma-associated hemophagocytic lymphohistiocytosis (HLH). The clinical and laboratory characteristics of 326 adult patients...
-
Article
Associations between metabolic profiles and incident CKD in the Chinese population aged 45–85 years
The roles of metabolic indices in predicting chronic kidney disease (CKD) were lacking. This study aimed to examine the concomitant impact of metabolic and novel anthropometric indices on incident CKD in the C...
-
Article
Open AccessMeasurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...
-
Article
Open AccessN6-methyladenosine modified TGFB2 triggers lipid metabolism reprogramming to confer pancreatic ductal adenocarcinoma gemcitabine resistance
Gemcitabine resistance is a major obstacle to the effectiveness of chemotherapy in pancreatic ductal adenocarcinoma (PDAC). Therefore, new strategies are needed to sensitize cancer cells to gemcitabine. Here, ...
-
Article
Open AccessLINC00525 enhances ZNF460-regulated CD24 expression through the sponge miR-125a-5p to promote malignant progression of breast cancer
CD24 is a highly glycosylated glycosylphosphatidylinositol anchored membrane protein that plays an important role in tumor progression. The aim of this study was to investigate the effect of abnormal expressio...
-
Article
Open AccessMiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice
Lipid droplet (LD)-laden microglia is a key pathological hallmark of multiple sclerosis. The recent discovery of this novel microglial subtype, lipid-droplet-accumulating microglia (LDAM), is notable for incre...
-
Article
Open AccessDevelopment and evaluation of machine learning models for predicting large-for-gestational-age newborns in women exposed to radiation prior to pregnancy
The correlation between radiation exposure before pregnancy and abnormal birth weight has been previously proven. However, for large-for-gestational-age (LGA) babies in women exposed to radiation before becomi...
-
Article
Non-uniform Solidification Behavior of Shell in Ultra-Large Beam Blank Mold
Non-uniform solidification of shell in continuous casting mold is the main cause of the high incidence of surface cracks of ultra-large beam blank (ULBB). To investigate the behaviors of the shell non-uniform ...
-
Article
Open AccessAssociation analyses of apolipoprotein E genotypes and cognitive performance in patients with Parkinson’s disease
Cognitive impairment is a common non-motor symptom of Parkinson’s disease (PD). The apolipoprotein E (APOE) ε4 genotype increases the risk of Alzheimer’s disease (AD). However, the effect of APOEε4 on cognitiv...
-
Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...