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Open AccessMultiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders
Cardio-metabolic disorders (CMDs) are common in aging people and are pivotal risk factors for cardiovascular diseases (CVDs). Inflammation is involved in the pathogenesis of CVDs and aging, but the underlying ...
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Article
Open AccessThe genome of a vestimentiferan tubeworm (Ridgeia piscesae) provides insights into its adaptation to a deep-sea environment
Vestimentifera (Polychaeta, Siboglinidae) is a taxon of deep-sea worm-like animals living in deep-sea hydrothermal vents, cold seeps, and organic falls. The morphology and lifespan of Ridgeia piscesae, which is t...
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Open AccessIntegrated analysis of microRNAs, circular RNAs, long non-coding RNAs, and mRNAs revealed competing endogenous RNA networks involved in brown adipose tissue whitening in rabbits
The brown adipose tissue (BAT) is a target for treating obesity. BAT losses thermogenic capacity and gains a “white adipose tissue-like” phenotype (“BAT whitening”) under thermoneutral environments, which is a...
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Open AccessIdentifying pleiotropic variants and candidate genes for fertility and reproduction traits in Holstein cattle via association studies based on imputed whole-genome sequence genotypes
Genetic progress for fertility and reproduction traits in dairy cattle has been limited due to the low heritability of most indicator traits. Moreover, most of the quantitative trait loci (QTL) and candidate g...
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Article
Open AccessIdentification of ARF family in blueberry and its potential involvement of fruit development and pH stress response
Auxin responsive factor (ARF) family is one of core components in auxin signalling pathway, which governs diverse developmental processes and stress responses. Blueberry is an economically important berry-bear...
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Open AccessGenome-wide identification and expression profile analysis of trihelix transcription factor family genes in response to abiotic stress in sorghum [Sorghum bicolor (L.) Moench]
Transcription factors, including trihelix transcription factors, play vital roles in various growth and developmental processes and in abiotic stress responses in plants. The trihelix gene has been systematically...
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Article
Open AccessCorrection to: Genome-wide development of insertiondeletion (InDel) markers for Cannabis and its uses in genetic structure analysis of Chinese germplasm and sex-linked marker identification
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Open AccessGenome-wide development of insertion-deletion (InDel) markers for Cannabis and its uses in genetic structure analysis of Chinese germplasm and sex-linked marker identification
Cannabis sativa L., a dioecious plant derived from China, demonstrates important medicinal properties and economic value worldwide. Cannabis properties have been usually harnessed depending on the sex of the plan...
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Genome-Wide Analysis of NAC Transcription Factors and Characterization of the Cold Stress Response in Sweet Osmanthus
Sweet osmanthus (Osmanthus fragrans) is an evergreen aromatic woody tree widely used in landsca**. However, O. fragrans is very sensitive to cold stress, which seriously limits its cultivation and application i...
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Article
Open AccessThe draft genome of horseshoe crab Tachypleus tridentatus reveals its evolutionary scenario and well-developed innate immunity
Horseshoe crabs are ancient marine arthropods with a long evolutionary history extending back approximately 450 million years, which may benefit from their innate immune systems. However, the genetic mechanism...
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Article
Zebrafish heart failure models: opportunities and challenges
Heart failure is a complex pathophysiological syndrome of pum** functional failure that results from injury, infection or toxin-induced damage on the myocardium, as well as genetic influence. Gene mutations ...
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Open AccessFlatfish monophyly refereed by the relationship of Psettodes in Carangimorphariae
The monophyly of flatfishes has not been supported in many molecular phylogenetic studies. The monophyly of Pleuronectoidei, which comprises all but one family of flatfishes, is broadly supported. However, the...
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Open AccessHigh throughput sequencing of small RNAs reveals dynamic microRNAs expression of lipid metabolism during Camellia oleifera and C. meiocarpa seed natural drying
Camellia species are ancient oilseed plants with a history of cultivation over two thousand years. Prior to oil extraction, natural seed drying is often practiced, a process affecting fatty acid quality and qu...
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Open AccessGenome-wide identification, phylogeny, and expression analysis of pectin methylesterases reveal their major role in cotton fiber development
Pectin methylesterase (PME, EC 3.1.1.11) is a hydrolytic enzyme that utilizes pectin as substrates, and plays a significant role in regulating pectin reconstruction thereby regulating plant growth. Pectin is o...
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Open AccessEfficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos
The RNA guided CRISPR/Cas9 nucleases have been proven to be effective for gene disruption in various animal models including Xenopus tropicalis. The neural crest (NC) is a transient cell population during embryon...
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Open AccessTargeted gene disruption in Xenopus laevis using CRISPR/Cas9
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Open AccessEvolution of multipartite mitochondrial genomes in the booklice of the genus Liposcelis (Psocoptera)
The genus Liposcelis (Psocoptera: Troctomorpha) has more than 120 species with a worldwide distribution and they pose a risk for global food security. The organization of mitochondrial (mt) genomes varies between...
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Open AccessGenomic, regulatory and epigenetic mechanisms underlying duplicated gene evolution in the natural allotetraploid Oryza minuta
Polyploid species contribute to Oryza diversity. However, the mechanisms underlying gene and genome evolution in Oryza polyploids remain largely unknown. The allotetraploid Oryza minuta, which is estimated to hav...
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Physiological and Molecular Responses to Salt Stress in Wild Emmer and Cultivated Wheat
Salinity severely influences growth and grain yield of wheat. Modern breeding efforts have contributed to severe loss of genetic diversity and reduced tolerance to salt stress in cultivated plants. Wild emmer ...
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Open AccessA proteome map of primary cultured rat Schwann cells
Schwann cells (SCs) are the principal glial cells of the peripheral nervous system with a wide range of biological functions. SCs play a key role in peripheral nerve regeneration and are involved in several he...