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  1. No Access

    Article

    Sequence and epigenetic variations of R2R3-MYB transcription factors determine the diversity of taproot skin and flesh colors in different cultivated types of radish (Raphanus sativus L.)

    This study found that three paralogous R2R3-MYB transcription factors exhibit functional divergence among different subspecies and cultivated types in radish.

    Qingbiao Wang, Yan** Wang, **angyu Wu, Wenyu Shi in Theoretical and Applied Genetics (2024)

  2. Article

    Open Access

    Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders

    Cardio-metabolic disorders (CMDs) are common in aging people and are pivotal risk factors for cardiovascular diseases (CVDs). Inflammation is involved in the pathogenesis of CVDs and aging, but the underlying ...

    Siting Wu, Yulin Li, Xue Zhao, Fu-Dong Shi, **gshan Chen in Clinical Proteomics (2024)

  3. Article

    Open Access

    Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor–immune hubs

    Spatially resolved gene expression profiling provides insight into tissue organization and cell–cell crosstalk; however, sequencing-based spatial transcriptomics (ST) lacks single-cell resolution. Current ST a...

    Siyu He, Yinuo **, Achille Nazaret, Lingting Shi, Xueer Chen in Nature Biotechnology (2024)

  4. No Access

    Article

    Development of SNP marker panels for genoty** by target sequencing (GBTS) and its application in soybean

    A high-throughput genoty** platform with customized flexibility, high genoty** accuracy, and low cost is critical for marker-assisted selection and genetic map** in soybean. Three assay panels were selec...

    Qing Yang, Jianan Zhang, **aolei Shi, Lei Chen, Jun Qin in Molecular Breeding (2023)

  5. No Access

    Article

    Regulated synthesis and metabolism of Monascus pigments in a unique environment

    Microbial fermentation in extreme environments is the focus of research, which provides new insights for the production and application of Monascus pigments. In this paper, the regulation of Monascus pigments met...

    Tao Li, Wenqian Zhao, Chengtao Wang, Kan Shi in World Journal of Microbiology and Biotechn… (2022)

  6. No Access

    Article

    Genome-wide association study of agronomic traits related to nitrogen use efficiency in wheat

    GWAS identified 347 QTLs associated with eight traits related to nitrogen use efficiency in a 389-count wheat panel. Four novel candidate transcription factor genes were verified using qRT-PCR.

    Huawei Shi, Ming Chen, Lifeng Gao, Yanxia Wang in Theoretical and Applied Genetics (2022)

  7. No Access

    Article

    Strategies for anti-oxidative stress and anti-acid stress in bioleaching of LiCoO2 using an acidophilic microbial consortium

    High metal ion concentrations and low pH cause severely inhibit the activity of an acidophilic microbial consortium (AMC) in bioleaching. This work investigated the effects of exogenous spermine on biofilm for...

    Dehong Liu, Hongjie Shi, Guanglin Chen, Xu Zhang, Tingyue Gu, Minglong Zhu in Extremophiles (2022)

  8. Article

    Open Access

    QTL identification, fine map**, and marker development for breeding peanut (Arachis hypogaea L.) resistant to bacterial wilt

    A major QTL, qBWA12, was fine mapped to a 216.68 kb physical region, and A12.4097252 was identified as a useful KASP marker for breeding peanut varieties resistant to bacterial wilt.

    Feiyan Qi, Ziqi Sun, Hua Liu, Zheng Zheng, Li Qin in Theoretical and Applied Genetics (2022)

  9. No Access

    Article

    Fine-map** and identification of a candidate gene controlling seed coat color in melon (Cucumis melo L. var. chinensis Pangalo)

    MELO3C019554 encoding a homeobox protein (PHD transcription factor) is a candidate gene that involved in the formation of seed coat color in melon.

    Zhicheng Hu, Xueyin Shi, Xuemiao Chen, **g Zheng in Theoretical and Applied Genetics (2022)

  10. Article

    Open Access

    Modular control of multiple pathways of Corynebacterium glutamicum for 5-aminolevulinic acid production

    5-aminolevulinic acid (ALA) has broad potential applications in the medical, agricultural and food industries. Several strategies have been implemented successfully to try to improve ALA synthesis. Nonetheless...

    Fanglan Ge, **aokun Li, Qingrong Ge, Di Zhu, Wei Li, Fenghui Shi in AMB Express (2021)

  11. No Access

    Article

    Identification and fine map** of qPBR10-1, a novel locus controlling panicle blast resistance in Pigm-containing P/TGMS line

    Rice blast is one of the most widespread and devastating diseases in rice production. Tremendous success has been achieved in the identification and characterization of genes and quantitative trait loci (QTLs)...

    Yunyu Wu, Ning **ao, Yuhong Li, Qiang Gao, Yuese Ning, Ling Yu in Molecular Breeding (2021)

  12. Article

    Open Access

    Identification of a novel immunological epitope on Hexon of fowl adenovirus serotype 4

    Fowl adenovirus serotype 4 (FAdV-4), the causative agent of hepatitis-hydropericardium syndrome (HHS), distributed widely in the poultry farms in China. Hexon is one of the major capsid proteins associated wit...

    **gyi Liu, Nan Mei, Yaling Wang, **n** Shi, Hongjun Chen in AMB Express (2021)

  13. No Access

    Article

    Natural variation of the Dt2 promoter controls plant height and node number in semi-determinant soybean

    Soybean (Glycine max (L.) Merrill) is an important legume crop worldwide. Plant height (PH) is a quantitative trait that is closely related to node number (NN) and internode length (IL) on the main stem, which to...

    Kun Kou, Tong Su, Yan** Wang, Hui Yang, Hao Du, Milan He, Tai Li in Molecular Breeding (2021)

  14. No Access

    Article

    Pseudomonas pratensis sp. nov., Isolated from Grassland Soil from Inner Mongolia, China

    A novel bacterial strain, designated MHJ-10JT, was isolated from a soil sample obtained from a grassland in Inner Mongolia, China. MHJ-10JT strain could grow at 4–37 °C (optimum: 30 °C) and pH 4–9 (optimum: pH 6)...

    Meng Zhang, Lixin Shen, Jiajia Shi, Linxia Chen, Ying Luo in Current Microbiology (2021)

  15. No Access

    Article

    Piriformospora indica colonization increases the growth, development, and herbivory resistance of sweet potato (Ipomoea batatas L.)

    Piriformospora indica symbiosis promoted the growth and photosynthesis, and simultaneously enhanced the resistance against insect herbivory by regulating sporamin-dependent defense in sweet potato.

    Qing Li, Yun-Wei Kuo, Kuan-Hung Lin, Weiqun Huang, Caisheng Deng in Plant Cell Reports (2021)

  16. No Access

    Article

    Evaluation of cowpea for drought tolerance at seedling stage

    Cowpea is a health-promoting diploid legume species [Vigna unguiculata (L.) Walp., 2n = 2x = 22]. The annual cowpea production is 5.4 million tons of dry seed globally. Despite the fact that cowpea is one of the ...

    Waltram Ravelombola, Ainong Shi, Senyu Chen, Haizheng **ong, Yufeng Yang in Euphytica (2020)

  17. No Access

    Article

    Rational modification of the carbon metabolism of Corynebacterium glutamicum to enhance l-leucine production

    l-Leucine is an essential amino acid that has wide and expanding applications in the industry. It is currently fast-growing market demand that provides a powerful impetus to further increase its bioconversion p.....

    Ying-Yu Wang, Ke Shi, Peidong Chen in Journal of Industrial Microbiology & Biote… (2020)

  18. No Access

    Article

    Nanobody against PDL1

    Programmed death ligand 1 (PDL1, CD274, B7-H1) has been identified as the ligand for the immune inhibitory receptor programmed death 1 protein (PD1/PDCD1). PDL1 is a member of B7 family of immune molecules and...

    Shufeng Li, Kunpeng Jiang, Ting Wang, Wei Zhang, Minke Shi in Biotechnology Letters (2020)

  19. Article

    Delivery of Helicobacter pylori HpaA to gastrointestinal mucosal immune sites using Lactococcus lactis and its immune efficacy in mice

    To develop a safe and effective oral vaccine against Helicobacter pylori using its HpaA protein expressed in Lactococcus lactis.

    Rongguang Zhang, Chen Wang, Wenbin Cheng, Guangcai Duan in Biotechnology Letters (2018)

  20. No Access

    Article

    Genetic engineering to alter carbon flux for various higher alcohol productions by Saccharomyces cerevisiae for Chinese Baijiu fermentation

    Higher alcohols significantly influence the quality and flavor profiles of Chinese Baijiu. ILV1-encoded threonine deaminase, LEU1-encoded α-isopropylmalate dehydrogenase, and LEU2-encoded β-isopropylmalate dehydr...

    Wei Li, Shi-Jia Chen, Jian-Hui Wang in Applied Microbiology and Biotechnology (2018)

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