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Article
Sequence and epigenetic variations of R2R3-MYB transcription factors determine the diversity of taproot skin and flesh colors in different cultivated types of radish (Raphanus sativus L.)
This study found that three paralogous R2R3-MYB transcription factors exhibit functional divergence among different subspecies and cultivated types in radish.
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Article
Open AccessMultiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders
Cardio-metabolic disorders (CMDs) are common in aging people and are pivotal risk factors for cardiovascular diseases (CVDs). Inflammation is involved in the pathogenesis of CVDs and aging, but the underlying ...
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Article
Open AccessStarfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor–immune hubs
Spatially resolved gene expression profiling provides insight into tissue organization and cell–cell crosstalk; however, sequencing-based spatial transcriptomics (ST) lacks single-cell resolution. Current ST a...
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Article
Development of SNP marker panels for genoty** by target sequencing (GBTS) and its application in soybean
A high-throughput genoty** platform with customized flexibility, high genoty** accuracy, and low cost is critical for marker-assisted selection and genetic map** in soybean. Three assay panels were selec...
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Article
Regulated synthesis and metabolism of Monascus pigments in a unique environment
Microbial fermentation in extreme environments is the focus of research, which provides new insights for the production and application of Monascus pigments. In this paper, the regulation of Monascus pigments met...
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Article
Genome-wide association study of agronomic traits related to nitrogen use efficiency in wheat
GWAS identified 347 QTLs associated with eight traits related to nitrogen use efficiency in a 389-count wheat panel. Four novel candidate transcription factor genes were verified using qRT-PCR.
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Article
Strategies for anti-oxidative stress and anti-acid stress in bioleaching of LiCoO2 using an acidophilic microbial consortium
High metal ion concentrations and low pH cause severely inhibit the activity of an acidophilic microbial consortium (AMC) in bioleaching. This work investigated the effects of exogenous spermine on biofilm for...
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Article
Open AccessQTL identification, fine map**, and marker development for breeding peanut (Arachis hypogaea L.) resistant to bacterial wilt
A major QTL, qBWA12, was fine mapped to a 216.68 kb physical region, and A12.4097252 was identified as a useful KASP marker for breeding peanut varieties resistant to bacterial wilt.
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Article
Fine-map** and identification of a candidate gene controlling seed coat color in melon (Cucumis melo L. var. chinensis Pangalo)
MELO3C019554 encoding a homeobox protein (PHD transcription factor) is a candidate gene that involved in the formation of seed coat color in melon.
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Article
Open AccessModular control of multiple pathways of Corynebacterium glutamicum for 5-aminolevulinic acid production
5-aminolevulinic acid (ALA) has broad potential applications in the medical, agricultural and food industries. Several strategies have been implemented successfully to try to improve ALA synthesis. Nonetheless...
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Article
Identification and fine map** of qPBR10-1, a novel locus controlling panicle blast resistance in Pigm-containing P/TGMS line
Rice blast is one of the most widespread and devastating diseases in rice production. Tremendous success has been achieved in the identification and characterization of genes and quantitative trait loci (QTLs)...
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Article
Open AccessIdentification of a novel immunological epitope on Hexon of fowl adenovirus serotype 4
Fowl adenovirus serotype 4 (FAdV-4), the causative agent of hepatitis-hydropericardium syndrome (HHS), distributed widely in the poultry farms in China. Hexon is one of the major capsid proteins associated wit...
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Article
Natural variation of the Dt2 promoter controls plant height and node number in semi-determinant soybean
Soybean (Glycine max (L.) Merrill) is an important legume crop worldwide. Plant height (PH) is a quantitative trait that is closely related to node number (NN) and internode length (IL) on the main stem, which to...
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Article
Pseudomonas pratensis sp. nov., Isolated from Grassland Soil from Inner Mongolia, China
A novel bacterial strain, designated MHJ-10JT, was isolated from a soil sample obtained from a grassland in Inner Mongolia, China. MHJ-10JT strain could grow at 4–37 °C (optimum: 30 °C) and pH 4–9 (optimum: pH 6)...
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Article
Piriformospora indica colonization increases the growth, development, and herbivory resistance of sweet potato (Ipomoea batatas L.)
Piriformospora indica symbiosis promoted the growth and photosynthesis, and simultaneously enhanced the resistance against insect herbivory by regulating sporamin-dependent defense in sweet potato.
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Article
Evaluation of cowpea for drought tolerance at seedling stage
Cowpea is a health-promoting diploid legume species [Vigna unguiculata (L.) Walp., 2n = 2x = 22]. The annual cowpea production is 5.4 million tons of dry seed globally. Despite the fact that cowpea is one of the ...
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Article
Rational modification of the carbon metabolism of Corynebacterium glutamicum to enhance l-leucine production
l-Leucine is an essential amino acid that has wide and expanding applications in the industry. It is currently fast-growing market demand that provides a powerful impetus to further increase its bioconversion p.....
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Article
Nanobody against PDL1
Programmed death ligand 1 (PDL1, CD274, B7-H1) has been identified as the ligand for the immune inhibitory receptor programmed death 1 protein (PD1/PDCD1). PDL1 is a member of B7 family of immune molecules and...
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Article
Delivery of Helicobacter pylori HpaA to gastrointestinal mucosal immune sites using Lactococcus lactis and its immune efficacy in mice
To develop a safe and effective oral vaccine against Helicobacter pylori using its HpaA protein expressed in Lactococcus lactis.
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Article
Genetic engineering to alter carbon flux for various higher alcohol productions by Saccharomyces cerevisiae for Chinese Baijiu fermentation
Higher alcohols significantly influence the quality and flavor profiles of Chinese Baijiu. ILV1-encoded threonine deaminase, LEU1-encoded α-isopropylmalate dehydrogenase, and LEU2-encoded β-isopropylmalate dehydr...