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  1. No Access

    Article

    Polymorphisms of the WRN gene and DNA damage of peripheral lymphocytes in age-related cataract in a Han Chinese population

    Werner syndrome is caused by mutations in the DNA repair Werner helicase (WRN) gene and characterized by accelerated aging including cataracts. Age-related cataract (ARC) cases (N = 504) and controls (N = 244) we...

    Shengqun Jiang, Nan Hu, **g Zhou, Junfang Zhang, Ruifang Gao, Jianyan Hu… in AGE (2013)

  2. Article

    Open Access

    RETRACTED ARTICLE: WRN inhibits oxidative stress-induced apoptosis of human lensepithelial cells through ATM/p53 signaling pathway and its expression is downregulated by DNA methylation

    Apoptosis and oxidative stress are the main etiology of age related cataract (ARC). This article aims to investigate the role of WRN in lens epithelial cells (LECs).

    Shengqun Jiang, Jiansu Chen in Molecular Medicine (2020)

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  3. Article

    Open Access

    Retraction Note to: WRN inhibits oxidative stress-induced apoptosis of human lensepithelial cells through ATM/p53 signaling pathway and its expression is downregulated by DNA methylation

    Shengqun Jiang, Jiansu Chen in Molecular Medicine (2021)

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