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Open AccessVirological investigation of four outbreaks of influenza B reassortants in the northern region of Taiwan from October 2006 to February 2007
From October 2006 to February 2007, clinical specimens from 452 patients with symptoms related to respiratory tract infection in the northern region of Taiwan were collected. Real-time PCR and direct immunoflu...
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Article
Open AccessCharacterization of a new murine cell line of sarcomatoid hepatocellular carcinoma and its application for biomarker/therapy development
Sarcomatoid hepatocellular carcinoma (SHC) is a rare type of HCC with significantly poorer survival than ordinary HCC. Little is known about the mechanism associated with SHC and its biomarkers and therapy. He...
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Article
Open AccessAntimicrobial resistance and genetic diversity in ceftazidime non-susceptible bacterial pathogens from ready-to-eat street foods in three Taiwanese cities
Bacterial contamination of ready-to-eat (RTE) street foods is a major concern worldwide. Dissemination of antibiotic resistant pathogens from food is an emerging public-health threat. To investigate the preval...
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Galectins in Host Defense Against Microbial Infections
Galectins are differentially expressed in a variety of cell types, including immune cells, and characterized by the affinity for β-galactoside–containing glycans. There are fifteen galectin members in mammals....
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Open AccessLate cART Initiation Consistently Driven by Late HIV Presentation: A Multicenter Retrospective Cohort Study in Taiwan from 2009 to 2019
Late initiation (LI) of combination antiretroviral therapy (cART)—defined as having a CD4+ count of < 200 cells/μL or an AIDS-defining disease at cART initiation—has detrimental outcomes but remains prevalent wo...
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Open AccessSex stratification of the trends and risk of mortality among individuals living with HIV under different transmission categories
We retrospectively examined 33,142 persons living with HIV (PLWH) in Taiwan from a nationwide database to assess sex-stratified trends and risk of all-cause mortality under different transmission categories fr...
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Open AccessCorrection to: Comparison of Virological Efficacy of DTG/ABC/3TG and B/F/TAF Regimens and Discontinuation Patterns in Persons Living with Advanced HIV in the Era of Rapid ART: A Retrospective Multicenter Cohort Study
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Open AccessComparison of Virological Efficacy of DTG/ABC/3TG and B/F/TAF Regimens and Discontinuation Patterns in Persons Living with Advanced HIV in the Era of Rapid ART: A Retrospective Multicenter Cohort Study
International treatment guidelines recommend the rapid initiation of antiretroviral therapy (ART) with bictegravir (B)/emtricitabine (F)/tenofovir alafenamide (TAF) and dolutegravir (DTG)-based regimens for tr...
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Article
Open AccessImpact of comorbidities on the serological response to COVID-19 vaccination in a Taiwanese cohort
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the best policies to control COVID-19 pandemic. The serological response to COVID-19 vaccination in Taiwanese patients...
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Article
Open AccessRole of mitochondrial alterations in human cancer progression and cancer immunity
Dysregulating cellular metabolism is one of the emerging cancer hallmarks. Mitochondria are essential organelles responsible for numerous physiologic processes, such as energy production, cellular metabolism, ...
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Open AccessEffectiveness and safety of direct oral anticoagulants versus warfarin in patients with atrial fibrillation and advanced kidney disease
The effectiveness and safety of direct oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) and advanced kidney disease (AKD) has not been fully established.
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Article
Open AccessAntibodies from dengue patients with prior exposure to Japanese encephalitis virus are broadly neutralizing against Zika virus
Exposure to multiple mosquito-borne flaviviruses within a lifetime is not uncommon; however, how sequential exposures to different flaviviruses shape the cross-reactive humoral response against an antigen from...
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Open AccessAuthor Correction: Antibodies from dengue patients with prior exposure to Japanese encephalitis virus are broadly neutralizing against Zika virus