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Article
Open AccessGWAS and Transcriptomic Analysis Identify OsRING315 as a New Candidate Gene Controlling Amylose Content and Gel Consistency in Rice
Cooking quality is the main factor determining the market value of rice. Although several major genes and a certain number of QTLs controlling cooking quality have been identified, the genetic complexity and e...
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Article
Cost-effectiveness analysis of bevacizumab for cerebral radiation necrosis treatment based on real-world utility value in China
Bevacizumab shows superior efficacy in cerebral radiation necrosis (CRN) therapy, but its economic burden remains heavy due to the high drug price. This study aims to evaluate the cost-effectiveness of bevaciz...
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Article
Machine learning-based non-destructive testing model for high precision and stable evaluation of mechanical properties in bamboo-wood composites
The efficient evaluation of mechanical performance of bamboo-wood composites (BWCs) is an important part for their development and application. To address the issues of low efficiency, high consumables usage, ...
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Article
Open AccessConstruction and validation of a clinical risk model based on machine learning for screening characteristic factors of lymphovascular space invasion in endometrial cancer
This study aimed to identify factors that affect lymphovascular space invasion (LVSI) in endometrial cancer (EC) using machine learning technology, and to build a clinical risk assessment model based on these ...
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Article
Open AccessEffect of nonsense-mediated mRNA decay factor SMG9 deficiency on premature aging in zebrafish
SMG9 is an essential component of the nonsense-mediated mRNA decay (NMD) machinery, a quality control mechanism that selectively degrades aberrant transcripts. Mutations in SMG9 are associated with heart and b...
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Article
Open AccessComparison of different treatment strategies for T3N1-3 stage gastric cancer based on the SEER database
Treatment options for T3N1 stage gastric cancer exhibit regional variation, with optimal approach remaining unclear. We derived our data from the SEER database, using Cox proportional risk regression models fo...
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Article
Open AccessIn vivo genome editing via CRISPR/Cas9-mediated homology-independent targeted integration for Bietti crystalline corneoretinal dystrophy treatment
Bietti crystalline corneoretinal dystrophy (BCD) is an autosomal recessive chorioretinal degenerative disease without approved therapeutic drugs. It is caused by mutations in CYP4V2 gene, and about 80% of BCD pat...
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Article
Study on Removal Rule of Impurity Elements in Preparation of Ferromolybdenum from Calcium Molybdate
Calcium molybdate is a waste produced by the molybdenum industry, and it is very feasible to replace part of molybdenum oxide with calcium molybdate for smelting by the carbon reduction method. In this paper, ...
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Article
Open AccessComplexity of avian evolution revealed by family-level genomes
Despite tremendous efforts in the past decades, relationships among main avian lineages remain heavily debated without a clear resolution. Discrepancies have been attributed to diversity of species sampled, ph...
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Article
Open AccessGene replacement therapy in Bietti crystalline corneoretinal dystrophy: an open-label, single-arm, exploratory trial
Bietti crystalline corneoretinal dystrophy is an inherited retinal disease caused by mutations in CYP4V2, which results in blindness in the working-age population, and there is currently no available treatment. H...
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Article
Review and Comparative Analysis of Factor of Safety Definitions in Slope Stability
There are several definitions of the factor of safety used to quantitatively characterize slope or landslide stability, which can yield varying results. A comprehensive comparison of the differences among vari...
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Article
Open AccessPangenome-Wide Association Study and Transcriptome Analysis Reveal a Novel QTL and Candidate Genes Controlling both Panicle and Leaf Blast Resistance in Rice
Cultivating rice varieties with robust blast resistance is the most effective and economical way to manage the rice blast disease. However, rice blast disease comprises leaf and panicle blast, which are differ...
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Article
Open AccessAdaptive expansion of ERVK solo-LTRs is associated with Passeriformes speciation events
Endogenous retroviruses (ERVs) are ancient retroviral remnants integrated in host genomes, and commonly deleted through unequal homologous recombination, leaving solitary long terminal repeats (solo-LTRs). Thi...
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Article
Study on the Dynamic Instantaneous Precipitation of ZK60-T4 Magnesium Alloy Under High Strain-Rate Loading
The commercial ZK60 magnesium alloy processed by solution heat treatment was dynamically loaded with a high strain rate by means of the split Hopkinson pressure bar (SHPB), and the dynamic instantaneous precip...
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Article
Open AccessThe Function of SD1 on Shoot Length and its Pyramiding Effect on Shoot Length and Plant Height in Rice (Oryza sativa L.)
Strong seedling vigor is imperative to achieve stable seedling establishment and enhance the competitiveness against weeds in rice direct seeding. Shoot length (SL) is one of the important traits associated wi...
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Article
A novel image deep learning–based sub-centimeter pulmonary nodule management algorithm to expedite resection of the malignant and avoid over-diagnosis of the benign
With the popularization of chest computed tomography (CT) screening, there are more sub-centimeter (≤ 1 cm) pulmonary nodules (SCPNs) requiring further diagnostic workup. This area represents an important oppo...
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Article
A review of the degradation of antibiotic contaminants using advanced oxidation processes: modification and application of layered double hydroxides based materials
In recent years, the treatment of organic pollutants has become a global concern due to the threat to human health posed by emerging contaminants, especially antibiotic contamination. Advanced oxidation proces...
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Article
Open AccessGene flow and an anomaly zone complicate phylogenomic inference in a rapidly radiated avian family (Prunellidae)
Resolving the phylogeny of rapidly radiating lineages presents a challenge when building the Tree of Life. An Old World avian family Prunellidae (Accentors) comprises twelve species that rapidly diversified at...
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Article
Open AccessApplication of gold immunochromatographic assay strip combined with digital evaluation for early detection of Toxoplasma gondii infection in multiple species
Timely diagnosis of Toxoplasma gondii infection is necessary to prevent and control toxoplasmosis transmission. The gold immunochromatographic assay (GICA) is a means of rapidly detecting pathogen in samples. GIC...
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Article
Correction to: Type I methanotrophs dominated methane oxidation and assimilation in rice paddy fields by the consequence of niche differentiation
