1,296 Result(s)
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Shao-**ong Wu
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Article
Open AccessFluvoxamine Exerts Sigma-1R to Rescue Autophagy via Pom121-Mediated Nucleocytoplasmic Transport of TFEB
Expansion of the GGGGCC-RNA repeat is a known cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), which currently have no cure. Recent studies have indicated the activation of Sigma...
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Open AccessUrinary concerns among older adults: a qualitative analysis in the context of healthy aging
Urinary concerns increase with age impacting health and quality of life. The aims of this study were to describe: (1) urinary concerns as an age-related change (ARC); (2) the challenges of urinary concerns; (3...
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Open AccessGenetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study
Rickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field and systematic investigations of various rickettsial organisms in Yunna...
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Reply to: “Is the TAE score a promising prognostic predictor for unresectable hepatocellular carcinoma treated with TACE plus lenvatinib with PD‑1 inhibitors? Further validation should be performed”
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Open AccessEstablishment of an ovarian cancer exhausted CD8+T cells-related genes model by integrated analysis of scRNA-seq and bulk RNA-seq
Ovarian cancer (OC) was the fifth leading cause of cancer death and the deadliest gynecological cancer in women. This was largely attributed to its late diagnosis, high therapeutic resistance, and a dearth of ...
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Potential Role of Dipeptidyl Peptidase−4 in Regulating Mitochondria and Oxidative Stress in Cardiomyocytes
Oxidative stress causes mitochondrial damage and bioenergetic dysfunction and inhibits adenosine triphosphate production, contributing to the pathogenesis of cardiac diseases. Dipeptidyl peptidase 4 (DPP4) is ...
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Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma
The clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma (ND-DLBCL) remains largely unexplored. One hundred ND-DLBCL patients were consecutively enrolled as training c...
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Open AccessQualitative study on the perception of good death in patients with end-stage cancer in oncology nurses
To explore the perception of good death of patients with end-stage cancer by nurses in the oncology department.
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From Perspective of Hippocampal Plasticity: Function of Antidepressant Chinese Medicine **aoyaosan
The hippocampus is one of the most commonly studied brain regions in the context of depression. The volume of the hippocampus is significantly reduced in patients with depression, which severely disrupts hippo...
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The effect of narrative nursing on improving the negative emotions and quality of life of patients with moderate to severe cancer pain
This study aimed to explore the effect of narrative nursing on improving the negative emotions, sleep quality, and quality of life of patients with moderate to severe cancer pain.
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Influence of pier height on the safety of trains running on high-speed railway bridges during earthquakes
Sudden earthquakes pose a threat to the running safety of trains on high-speed railway bridges, and the stiffness of piers is one of the factors affecting the dynamic response of train-track-bridge system. In ...
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Perspectives on the involvement of the gut microbiota in salt-sensitive hypertension
Salt-sensitivity hypertension (SSH) is an independent predictor of cardiovascular event-related death. Despite the extensiveness of research on hypertension, which covers areas such as the sympathetic nervous ...
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Open AccessEnantioselective copper-catalyzed azidation/click cascade reaction for access to chiral 1,2,3-triazoles
Chiral 1,2,3-triazoles are highly attractive motifs in various fields. However, achieving catalytic asymmetric click reactions of azides and alkynes for chiral triazole synthesis remains a significant challeng...
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Integrating numerical techniques and predictive diagnosis for precision enhancement in roller cam rotary table
Currently, various industries are increasingly trending towards multi-axis machining and Industry 4.0. As a result, the demand for machining flexibility, speed, and precision in machine tools is also rising. D...
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The Crystallization Behavior of L-Poly(lactic acid)/Polypropylene Blends: The Acceleration for Both L-Poly(lactic acid) and Polypropylene
For a polymer/polymer dismissible blend with two crystallizable components, the crystallization behavior of different components and the reciprocal influences between different crystals are interesting and imp...
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A Bregman-Style Improved ADMM and its Linearized Version in the Nonconvex Setting: Convergence and Rate Analyses
This work explores a family of two-block nonconvex optimization problems subject to linear constraints. We first introduce a simple but universal Bregman-style improved alternating direction method of multipli...
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Open AccessHBB contributes to individualized aconitine-induced cardiotoxicity in mice via interfering with ABHD5/AMPK/HDAC4 axis
The root of Aconitum carmichaelii Debx. (Fuzi) is an herbal medicine used in China that exerts significant efficacy in rescuing patients from severe diseases. A key toxic compound in Fuzi, aconitine (AC), could t...
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Crevice corrosion of reinforcing steel in carbonated simulated concrete pore solutions contaminated by chloride
The crevice corrosion of the reinforcing steel in the carbonated simulated concrete pore solutions (SCPSs) containing 0.04 mol/L chloride was investigated. In comparison, the steel without crevice covered on i...
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The risk of free flap revision and subsequent medical costs in patients with hypopharyngeal cancer
Few studies have examined the preoperative risks and healthcare costs related to free flap revision in hypopharyngeal cancer (HPC) patients.
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Open AccessFerroptosis: a potential bridge linking gut microbiota and chronic kidney disease
Ferroptosis is a novel form of lipid peroxidation-driven, iron-dependent programmed cell death. Various metabolic pathways, including those involved in lipid and iron metabolism, contribute to ferroptosis regu...
