3 Result(s)
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Article
The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel spike protein mutations that are influencing the epidemiological and clinical aspects of the COVID-19 pandemic. These vari...
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Protocol
Evolution of Viral Genomes: Interplay Between Selection, Recombination, and Other Forces
RNA viruses evolve very rapidly, often recombine, and are subject to strong host (immune response) and anthropogenic (antiretroviral drugs) selective forces. Given their compact and extensively sequenced genom...
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Protocol
Detecting Signatures of Selection from DNA Sequences Using Datamonkey
Natural selection is a fundamental process affecting all evolving populations. In the simplest case, positive selection increases the frequency of alleles that confer a fitness advantage relative to the rest o...
