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  1. Article

    Open Access

    Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa

    Three lineages (BA.1, BA.2 and BA.3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa’s fourth Coronavirus Disease 2019 (COVID-19)...

    Houriiyah Tegally, Monika Moir, Josie Everatt, Marta Giovanetti in Nature Medicine (2022)

  2. Article

    Open Access

    Human HspB1, HspB3, HspB5 and HspB8: Sha** these disease factors during vertebrate evolution

    Small heat shock proteins (sHSPs) emerged early in evolution and occur in all domains of life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, HspB5, HspB8) are associated wi...

    Rainer Benndorf, Ryan Velazquez, Jordan D. Zehr in Cell Stress and Chaperones (2022)

  3. Article

    The biological and clinical significance of emerging SARS-CoV-2 variants

    The past several months have witnessed the emergence of SARS-CoV-2 variants with novel spike protein mutations that are influencing the epidemiological and clinical aspects of the COVID-19 pandemic. These vari...

    Kaiming Tao, Philip L. Tzou, Janin Nouhin, Ravindra K. Gupta in Nature Reviews Genetics (2021)