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Article
Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer
Epithelial-mesenchymal transition (EMT) is a driving force in promoting malignant cancer, including initiation, growth, and metastasis. EMT is a dynamic process that can undergo a mesenchymal-epithelial transi...
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Article
Correction: High-risk additional chromosomal abnormalities at low blast counts herald death by CML
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessHigh-risk additional chromosomal abnormalities at low blast counts herald death by CML
Blast crisis is one of the remaining challenges in chronic myeloid leukemia (CML). Whether additional chromosomal abnormalities (ACAs) enable an earlier recognition of imminent blastic proliferation and a time...
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Article
Open AccessDefining therapy goals for major molecular remission in chronic myeloid leukemia: results of the randomized CML Study IV
Major molecular remission (MMR) is an important therapy goal in chronic myeloid leukemia (CML). So far, MMR is not a failure criterion according to ELN management recommendation leading to uncertainties when t...