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    Article

    Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer

    Epithelial-mesenchymal transition (EMT) is a driving force in promoting malignant cancer, including initiation, growth, and metastasis. EMT is a dynamic process that can undergo a mesenchymal-epithelial transi...

    Hector Esquer, Qiong Zhou, Travis Nemkov, Adedoyin D. Abraham in Oncogene (2021)

  2. Article

    Correction: High-risk additional chromosomal abnormalities at low blast counts herald death by CML

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Rüdiger Hehlmann, Astghik Voskanyan, Michael Lauseker, Markus Pfirrmann in Leukemia (2020)

  3. Article

    Open Access

    High-risk additional chromosomal abnormalities at low blast counts herald death by CML

    Blast crisis is one of the remaining challenges in chronic myeloid leukemia (CML). Whether additional chromosomal abnormalities (ACAs) enable an earlier recognition of imminent blastic proliferation and a time...

    Rüdiger Hehlmann, Astghik Voskanyan, Michael Lauseker, Markus Pfirrmann in Leukemia (2020)

  4. Article

    Open Access

    Defining therapy goals for major molecular remission in chronic myeloid leukemia: results of the randomized CML Study IV

    Major molecular remission (MMR) is an important therapy goal in chronic myeloid leukemia (CML). So far, MMR is not a failure criterion according to ELN management recommendation leading to uncertainties when t...

    Susanne Saussele, Rüdiger Hehlmann, Alice Fabarius, Sabine Jeromin in Leukemia (2018)