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  1. Article

    Open Access

    Trajectories of physical activity, from young adulthood to older adulthood, and pancreatic cancer risk; a population-based case-control study in Ontario, Canada

    There is inconsistent evidence on the association between physical activity and pancreatic cancer risk and few studies have investigated early life or life-course physical activity. The objective of this study...

    Jaspreet Sandhu, Vanessa De Rubeis, Michelle Cotterchio, Brendan T. Smith in BMC Cancer (2020)

  2. Article

    Open Access

    Trajectories of body mass index, from adolescence to older adulthood, and pancreatic cancer risk; a population-based case–control study in Ontario, Canada

    Pancreatic cancer has the highest fatality rate of all cancers. Adulthood obesity is an established risk factor for pancreatic cancer; however, life-course obesity is not well understood. The aim of this study...

    Vanessa De Rubeis, Michelle Cotterchio, Brendan T. Smith in Cancer Causes & Control (2019)

  3. No Access

    Article

    Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids

    Human pluripotent stem cells can be differentiated into exocrine pancreas progenitor organoids, allowing studies of development and pancreatic cancer modeling.

    Ling Huang, Audrey Holtzinger, Ishaan Jagan, Michael BeGora, Ines Lohse in Nature Medicine (2015)

  4. Article

    Open Access

    Medial open transversus abdominis plane (MOTAP) catheters for analgesia following open liver resection: study protocol for a randomized controlled trial

    The current standard for pain control following liver surgery is intravenous, patient-controlled analgesia (IV PCA) or epidural analgesia. We have developed a modification of a regional technique called medial...

    Paul Karanicolas, Sean Cleary, Paul McHardy, Stuart McCluskey, Jason Sawyer in Trials (2014)