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  1. No Access

    Article

    Map** O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody

    The microtubule-associated protein tau is known to be post-translationally modified by the addition of N-acetyl-d-glucosamine monosaccharides to certain serine and threonine residues. These O-GlcNAc modification ...

    Scott A. Yuzwa, Anuj K. Yadav, Yuliya Skorobogatko, Thomas Clark… in Amino Acids (2011)

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    Protocol

    Production of O-GlcNAc Modified Recombinant Tau in E. coli and Detection of Ser400 O-GlcNAc Tau In Vivo

    Assembly of the microtubule-associated protein tau (tau) into paired helical filaments that ultimately give rise to neurofibrillary tangles (NFTs) makes up one half of the two hallmark pathologies of Alzheimer...

    Scott A. Yuzwa, David J. Vocadlo in Tau Protein (2017)

  3. No Access

    Article

    Culture Protocol and Transcriptomic Analysis of Murine SVZ NPCs and OPCs

    The mammalian adult brain contains two neural stem and precursor (NPC) niches: the subventricular zone [SVZ] lining the lateral ventricles and the subgranular zone [SGZ] in the hippocampus. From these, SVZ NP...

    Nicole L. Dittmann, Pouria Torabi, Adrianne E. S. Watson… in Stem Cell Reviews and Reports (2023)

  4. Article

    Open Access

    LRIG1 controls proliferation of adult neural stem cells by facilitating TGFβ and BMP signalling pathways

    Adult Neural Stem Cells (aNSCs) in the ventricular-subventricular zone (V-SVZ) are largely quiescent. Here, we characterize the mechanism underlying the functional role of a cell-signalling inhibitory protein,...

    Stephanie Ouzikov, Kyshona M. Edwards, Tanvi Anandampillai… in Communications Biology (2024)

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