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Open AccessMultiple endocrine neoplasia type 2B diagnosed after small intestinal volvulus with progressive megacolon in an adolescent
Multiple endocrine neoplasia type 2B is a rare autosomal dominant disease characterized by the presence of medullary thyroid carcinoma, pheochromocytoma, Marfan-like fatigue, a peculiar face with thickening of...
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Article
Open AccessProgress testing of an objective structured clinical examination during undergraduate clinical clerkship: a mixed-methods pilot study
Progress testing is an assessment method in which an examination reflecting competencies at graduation is regularly administered to students over multiple years, thereby facilitating self-directed learning. Ho...
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Open AccessRationale and study design of a randomized controlled trial to investigate the renoprotective effect of canagliflozin assessed by test of renal hemodynamics in diabetic kidney disease (the FAGOTTO study)
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are considered to have the potential to maintain renal function by correcting glomerular hypertension in patients with diabetic kidney disease (DKD). The aim ...
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Open AccessEvaluating glucose variability through OGTT in early pregnancy and its association with hypertensive disorders of pregnancy in non-diabetic pregnancies: a large-scale multi-center retrospective study
Recent evidence suggests increased glucose variability (GV) causes endothelial dysfunction, a central pathology of hypertensive disorders of pregnancy (HDP). We aimed to investigate the association between GV ...
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Open AccessEffect of body mass index on the association between alcohol consumption and the development of chronic kidney disease
The influence of body mass or metabolic capacity on the association between alcohol consumption and lower risks of develo** chronic kidney disease (CKD) is not fully elucidated. We examined whether the body ...
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Open AccessRationale and study design of a randomized controlled trial for development of a treatment strategy for chronic kidney disease–mineral and bone disorder by multilateral mechanism of etelcalcetide hydrochloride (the DUET study)
Secondary hyperparathyroidism (SHPT) is a common complication in advanced chronic kidney disease (CKD). The aims of this study are to clarify the efficacy of etelcalcetide, a novel-approved intravenous calcimi...
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Open AccessClinical impact of endocapillary proliferation according to the Oxford classification among adults with Henoch-Schönlein purpura nephritis: a multicenter retrospective cohort study
Henoch-Schönlein purpura nephritis (HSPN) is a form of small vessel vasculitis associated with purpura and IgA deposition in the glomeruli. The International Study of Kidney Disease in Children (ISKDC) classif...
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Open AccessFactors associated with employment in patients undergoing hemodialysis: a mixed methods study
For patients undergoing hemodialysis, continuing in labor is very challenging and many patients have difficulty in current and/or previous workplaces. The objective of the present study is to clarify the deter...
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Erratum to: Validation of the equations for estimating daily sodium excretion from spot urine in patients with chronic kidney disease