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  1. No Access

    Chapter

    Introduction

    The bioanalysis of biopharmaceuticals is central to the drug development process. The efficacious dose projections of biopharmaceuticals rely on a robust, sensitive, specific, and selective bioanalytical assay...

    Sanjeev Bhardwaj, Inderpal Singh… in An Introduction to Bioanalysis of Biopharm… (2022)

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    Chapter

    An Introduction to Bioanalysis of Monoclonal Antibodies

    Therapeutic monoclonal antibodies are one of the largest and fastest growing class of large-molecule biotherapeutics. Accurate and reliable quantification of these biotherapeutics in biological matrix is manda...

    Varun Ramani, Sanjeev Bhardwaj… in An Introduction to Bioanalysis of Biopharm… (2022)

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    Chapter

    An Introduction to Bioanalysis of Bispecific and Fusion Proteins

    Bispecific antibodies and fusion proteins are part of the next generation of biotherapeutics that contain more than one functional domain. These biotherapeutic modalities are structurally complex and require u...

    Kelly Covert, Hongmei Niu, Sanjeev Bhardwaj in An Introduction to Bioanalysis of Biopharm… (2022)

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    Article

    GABA agonists and neurotransmitters metabolizing enzymes in steroid-primed OVX rats

    The effect of intraventricular (IVT) administration of GABAA receptor agonist muscimol and GABAB receptor agonist, baclofen was examined on the activity of acetylcholinesterase (AChE), monoamine oxidase (MAO) ...

    Gurcharan Kaur, Poonam Sharma, Sanjeev Bhardwaj… in Molecular and Cellular Biochemistry (1997)