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  1. Article

    Open Access

    Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1α and HIF-2α target genes

    Activating KRAS mutations are important for cancer initiation and progression; and have recently been shown to cause primary resistance to therapies targeting the epidermal growth factor receptor. Therefore, stra...

    Sang Y Chun, Craig Johnson, Joseph G Washburn, Marcia R Cruz-Correa… in Molecular Cancer (2010)

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