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    Article

    The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm

    Activation of the 5-lipoxygenase (5-LO) pathway leads to the biosynthesis of proinflammatory leukotriene lipid mediators. Genetic studies have associated 5-LO and its accessory protein, 5-LO-activating protein...

    Lei Zhao, Michael P W Moos, Rolf Gräbner, Frédérique Pédrono, **** Fan… in Nature Medicine (2004)