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    Article

    Utility of cardiac computed tomography for evaluation of pannus in mechanical aortic valve

    The clinical significance of pannus detected on computed tomography (CT) has not yet been investigated. The purposes of this study were to investigate the clinical significance of pannus detected on cardiac CT...

    Young Joo Suh, Young ** Kim, Sak Lee in The International Journal of Cardiovascula… (2015)

  2. Article

    Open Access

    Impact of prosthesis-patient mismatch after mitral valve replacement in rheumatic population: Does mitral position prosthesis-patient mismatch really exist?

    Prosthesis-patient mismatch (PPM) is characterised by the effects of inadequate prosthesis size relative to body surface area (BSA).The purpose of this study was to determine the impact of PPM on late clinical...

    Seung Hyun Lee, Byung Chul Chang, Young-Nam Youn in Journal of Cardiothoracic Surgery (2017)

  3. Article

    Open Access

    The effect of perioperative intravenously administered iron isomaltoside 1000 (Monofer®) on transfusion requirements for patients undergoing complex valvular heart surgery: study protocol for a randomized controlled trial

    Anemia is a frequent complication after cardiac surgery especially following reoperation due to previous prosthetic valve failure or multiple valve surgery (including combined coronary artery bypass grafting)....

    Seung Hyun Lee, Jae-Kwang Shim, Sarah Soh, Jong Wook Song, Byung Chul Chang in Trials (2018)

  4. Article

    Open Access

    Prognostic role of serum high mobility group box 1 concentration in cardiac surgery

    Outcomes of cardiac surgery are influenced by systemic inflammation. High mobility group box 1 (HMGB1), a pivotal inflammatory mediator, plays a potential role as a prognostic biomarker in cardiovascular disea...

    Namo Kim, Sak Lee, Jeong-Rim Lee, Young-Lan Kwak, Ji-Hae Jun in Scientific Reports (2020)

  5. No Access

    Article

    Differentiation of left atrial appendage thrombus from circulatory stasis using cardiac CT radiomics in patients with valvular heart disease

    To determine whether quantitative radiomic features from cardiac CT could differentiate the left atrial appendage (LAA) thrombus from circulatory stasis in patients with valvular heart disease.

    Sei Hyun Chun, Young Joo Suh, Kyunghwa Han, Sang Joon Park in European Radiology (2021)

  6. Article

    Open Access

    Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia

    Valvular inflammation triggered by hyperlipidemia has been considered as an important initial process of aortic valve disease; however, cellular and molecular evidence remains unclear. Here, we assess the rela...

    Seung Hyun Lee, Nayoung Kim, Minkyu Kim, Sang-Ho Woo, Inhee Han in Nature Communications (2022)